Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential

Purine Metabolism Dysfunctions: Experimental Methods of Detection and Diagnostic Potential

Purines, such as adenine and guanine, perform several important functions in the cell. They are found in nucleic acids; are structural components of some coenzymes, including NADH and coenzyme A; and have a crucial role in the modulation of energy metabolism and signal transduction. Moreover, purine...

Full description

Bibliographic Details
Main Authors:	Arrigo F. G. Cicero, Federica Fogacci, Valentina Di Micoli, Cristina Angeloni, Marina Giovannini, Claudio Borghi
Format:	Article
Language:	English
Published:	MDPI AG 2023-04-01
Series:	International Journal of Molecular Sciences
Subjects:	uric acid allantoin xanthine purine metabolism
Online Access:	https://www.mdpi.com/1422-0067/24/8/7027

Similar Items

Purine metabolism state in patients with type 1 diabetes mellitus
by: A. O. Cherniaieva, et al.
Published: (2023-04-01)

Therapeutic Strategies for the Treatment of Chronic Hyperuricemia: An Evidence-Based Update
by: Arrigo F. G. Cicero, et al.
Published: (2021-01-01)

Postmortem Alteration of Purine Metabolism in Coronary Artery Disease
by: Phakchira Somtua, et al.
Published: (2023-11-01)

Effect of ryegrass hay and ryegrass silage, cut at two stages of development, on nutrient digestibility, nitrogen balance, and purine derivative excretion in growing sheep
by: Manuel Gonzalez-Ronquillo, et al.
Published: (2021-01-01)

Diurnal Variations in Serum Uric Acid, Xanthine, and Xanthine Oxidoreductase Activity in Male Patients with Coronary Artery Disease
by: Megumi Shimizu, et al.
Published: (2023-10-01)

Inborn Errors of Purine Salvage and Catabolism
by: Marcella Camici, et al.
Published: (2023-06-01)

Analysis of parameters of purine metabolism in patients with diabetes mellitus type 2
by: A.O. Chernyaeva, et al.
Published: (2023-12-01)

Combinatorial co-expression of xanthine dehydrogenase and chaperone XdhC from Acinetobacter baumannii and Rhodobacter capsulatus and their applications in decreasing purine content in food
by: Chenghua Wang, et al.
Published: (2023-07-01)

A Novel Purine and Uric Metabolism Signature Predicting the Prognosis of Hepatocellular Carcinoma
by: Shengjie Yang, et al.
Published: (2022-07-01)

The clinical diagnostic value of a study of the activity of enzymes of the guanyl branch of purine metabolism in patients with ankylosing spondyloarthritis
by: Aleksandr Borisovich Zborovskiy, et al.
Published: (2010-04-01)

Disorder of purine metabolism in the etiopathogenesis of urate nephrolithiasis
by: S. I. Vorotyntsev, et al.
Published: (2023-04-01)

Combined Metabolomic and Transcriptomic Analysis Reveals Allantoin Enhances Drought Tolerance in Rice
by: Shuai Lu, et al.
Published: (2022-11-01)

Effects of purine nucleotide administration on purine nucleotide metabolism in brains of heroin-dependent rats
by: Kun Li, et al.

Indicators of phagocytic activity, autosensibilization and purine metabolism in patients with pneumoconiosis
by: S. S. Boieva, et al.
Published: (2018-07-01)

Electrochemical Analysis of the Influence of Purines on Copper, Steel and Some Other Metals Corrosion
by: Marija B. Petrović Mihajlović, et al.
Published: (2022-07-01)

Uric Acid and Hypertension: Prognostic Role and Guide for Treatment
by: Federica Piani, et al.
Published: (2021-01-01)

Germ-Free Conditions Modulate Host Purine Metabolism, Exacerbating Adenine-Induced Kidney Damage
by: Eikan Mishima, et al.
Published: (2020-08-01)

Balanço de compostos nitrogenados, produção de proteína microbiana e concentração plasmática de uréia em vacas leiteiras alimentadas com dietas à base de cana-de-açúcar Nitrogenous compounds balance, microbial protein production and plasma urea concentration in dairy cows fed sugar cane based diets
by: Sandro de Souza Mendonça, et al.
Published: (2004-04-01)

Diagnostic value of determining the level of purine metabolism intermediates in pregnant women with chronic hypertension and superimposed preeclampsia
by: Dinara Omertayeva, et al.
Published: (2021-07-01)

Optimization Of Elevating Blood Uric Acid Levels With High Purine Diet
by: Fitria Rahmawati, et al.
Published: (2018-01-01)

Potential Probiotic <i>Lacticaseibacillus paracasei</i> MJM60396 Prevents Hyperuricemia in a Multiple Way by Absorbing Purine, Suppressing Xanthine Oxidase and Regulating Urate Excretion in Mice
by: Youjin Lee, et al.
Published: (2022-04-01)

Differential regulation of hypoxanthine and xanthine by obesity in a general population
by: Masato Furuhashi, et al.
Published: (2020-07-01)

Purine and pyrimidine nucleotide metabolism in Mollicutes
by: Cristiano Valim Bizarro, et al.
Published: (2007-01-01)

High Performance Liquid Chromatography Analysis and Description of Purine Content of Diets Suitable for Dogs with <i>Leishmania</i> Infection during Allopurinol Treatment—A Pilot Trial
by: Melanie Kaempfle, et al.
Published: (2023-09-01)

Antibiotic-induced gut microbiota dysbiosis has a functional impact on purine metabolism
by: Xin Liu, et al.
Published: (2023-07-01)

Purine metabolism in plant pathogenic fungi
by: Manli Sun, et al.
Published: (2024-02-01)

Purine-Induced IFN-γ Promotes Uric Acid Production by Upregulating Xanthine Oxidoreductase Expression
by: Huanhuan Wang, et al.
Published: (2022-01-01)

The Intersection of Purine and Mitochondrial Metabolism in Cancer
by: Humberto De Vitto, et al.
Published: (2021-09-01)

Targeting purine metabolism in ovarian cancer
by: Jingchun Liu, et al.
Published: (2022-08-01)

Research Advances in Purine Phosphoribosyltransferases of Protozoan Parasites
by: Zhihui YU, et al.
Published: (2023-08-01)

Towards the Use of Adsorption Methods for the Removal of Purines from Beer
by: Catarina Almeida, et al.
Published: (2021-10-01)

Studies of the purine biosynthetic pathways in the gastrointestinal tract.
by: LeLeiko, Neal Simon
Published: (2014)

Purines and Adenosine Receptors in Osteoarthritis
by: Bruce N. Cronstein, et al.
Published: (2023-12-01)

Purine metabolism promotes radioresistance and is a therapeutic target in glioblastoma
by: Weihua Zhou, et al.
Published: (2020-11-01)

Purine signaling pathway dysfunction in autism spectrum disorders: Evidence from multiple omics data
by: Si Dai, et al.
Published: (2023-02-01)

Activity of xanthine oxidase in plasma correlates with indices of insulin resistance and liver dysfunction in patients with type 2 diabetes mellitus and metabolic syndrome: A pilot exploratory study
by: Sumito Sunagawa, et al.
Published: (2019-01-01)

Possibilities of the use of fast scan voltammetry in simultaneous determination of purines at carbon fiber ultramicroelectrodes
by: Cavalheiro Éder T. G., et al.
Published: (2000-01-01)

Yeast to Study Human Purine Metabolism Diseases
by: Bertrand Daignan-Fornier, et al.
Published: (2019-01-01)

Potential Mechanisms Connecting Purine Metabolism and Cancer Therapy
by: Jie Yin, et al.
Published: (2018-07-01)

Search of protein kinase CK2 inhibitors based on purine-2,6-diones derivatives
by: M. V. Protopopov, et al.
Published: (2017-10-01)