Optimised Electroporation for Loading of Extracellular Vesicles with Doxorubicin

Optimised Electroporation for Loading of Extracellular Vesicles with Doxorubicin

The clinical use of chemotherapeutics is limited by several factors, including low cellular uptake, short circulation time, and severe adverse effects. Extracellular vesicles (EVs) have been suggested as a drug delivery platform with the potential to overcome these limitations. EVs are cell-derived,...

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Bibliographic Details
Main Authors: Angus J. Lennaárd, Doste R. Mamand, Rim Jawad Wiklander, Samir EL Andaloussi, Oscar P. B. Wiklander
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pharmaceutics
Subjects:
extracellular vesicles
exosomes
doxorubicin
optimisation
electroporation
loading
Online Access:https://www.mdpi.com/1999-4923/14/1/38

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