Decrease of virulence for BALB/c mice produced by continuous subculturing <it>of Nocardia brasiliensis</it>

Decrease of virulence for BALB/c mice produced by continuous subculturing <it>of Nocardia brasiliensis</it>

<p>Abstract</p> <p>Background</p> <p>Subculturing has been extensively used to attenuate human pathogens. In this work we studied the effect of continuous subculturing of <it>Nocardia brasiliensis </it>HUJEG-1 on virulence in a murine model.</p> <p&...

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Bibliographic Details
Main Authors: Ocampo-Candiani Jorge, Romero-Díaz Víktor J, Said-Fernández Salvador, Lozano-Garza Hector G, Welsh Oliverio, Almaguer-Chávez Janeth A, Vera-Cabrera Lucio
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Infectious Diseases
Subjects:
Mycetoma
Nocardia
attenuation
Online Access:http://www.biomedcentral.com/1471-2334/11/290

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