Role of the fatty pancreatic infiltration in pancreatic oncogenesis

Role of the fatty pancreatic infiltration in pancreatic oncogenesis

Abstract Although pancreatic precancerous lesions are known to be related to obesity and fatty pancreatic infiltration, the mechanisms remain unclear. We assessed the role of fatty infiltration in the process of pancreatic oncogenesis and obesity. A combined transcriptomic, lipidomic and pathologica...

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Main Authors: Sonia Frendi, Chloé Martineau, Hélène Cazier, Rémy Nicolle, Anaïs Chassac, Miguel Albuquerque, Jérôme Raffenne, Julie Le Faouder, Valérie Paradis, Jérôme Cros, Anne Couvelard, Vinciane Rebours
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Obesity
Intra-lobular and extra-lobular fatty pancreatic infiltration
Pancreatic precancerous lesions
Lipidomic MALDI-TOF imaging mass spectrometry
Pancreatic oncogenesis
Online Access:https://doi.org/10.1038/s41598-024-57294-6

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