ROS/mtROS promotes TNTs formation via the PI3K/AKT/mTOR pathway to protect against mitochondrial damages in glial cells induced by engineered nanomaterials

ROS/mtROS promotes TNTs formation via the PI3K/AKT/mTOR pathway to protect against mitochondrial damages in glial cells induced by engineered nanomaterials

Abstract Background As the demand and application of engineered nanomaterials have increased, their potential toxicity to the central nervous system has drawn increasing attention. Tunneling nanotubes (TNTs) are novel cell–cell communication that plays a crucial role in pathology and physiology. How...

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Bibliographic Details
Main Authors: Xinpei Lin, Wei Wang, Xiangyu Chang, Cheng Chen, Zhenkun Guo, Guangxia Yu, Wenya Shao, Siying Wu, Qunwei Zhang, Fuli Zheng, Huangyuan Li
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Particle and Fibre Toxicology
Subjects:
Cobalt nanoparticles
Titanium dioxide nanoparticles
Multi-walled carbon nanotubes
Tunneling nanotubes
ROS
mtROS
Online Access:https://doi.org/10.1186/s12989-024-00562-0

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