Development of a Glycerol-Inducible Expression System for High-Yield Heterologous Protein Production in Bacillus subtilis

Development of a Glycerol-Inducible Expression System for High-Yield Heterologous Protein Production in Bacillus subtilis

ABSTRACT The development of efficient, low-cost, and robust expression systems is important for the mass production of proteins and natural products in large amounts using cell factories. Glycerol is an ideal carbon source for large-scale fermentation due to its low cost and favorable maintenance of...

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Bibliographic Details
Main Authors: Laichuang Han, Qiaoqing Chen, Jie Luo, Wenjing Cui, Zhemin Zhou
Format: Article
Language:English
Published: American Society for Microbiology 2022-10-01
Series:Microbiology Spectrum
Subjects:
glycerol-inducible expression system
Bacillus subtilis
antiterminator protein
nattokinase
hybrid promoter
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01322-22

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