HER2 induces expression of leptin in human breast epithelial cells

HER2 induces expression of leptin in human breast epithelial cells

A close association between the obesity hormone leptin andbreast cancer progression has been suggested. The presentstudy investigated the molecular mechanism for enhancedleptin expression in breast cancer cells and its functionalsignificance in breast cancer aggressiveness. We examinedwhether leptin...

Full description

Bibliographic Details
Main Author:	Aree Moon
Format:	Article
Language:	English
Published:	Korean Society for Biochemistry and Molecular Biology 2012-12-01
Series:	BMB Reports
Subjects:	Breast cancer ErBb2 HER2 Leptin
Online Access:	http://www.jbmb.or.kr/jbmb/pdf.php?data=MTMwMTE0MTVAcGRmX3JhaW50cmFjZV9sZWV5c0AlNUI0NS0xMiU1RDEyMTIyNjE2MzJfJTI4NzE5LTcyMyUyOUJNQl8xMi0xNjQucGRm

Similar Items

Epigenetic Silencing of HER2 Expression during Epithelial-Mesenchymal Transition Leads to Trastuzumab Resistance in Breast Cancer
by: Babak Nami, et al.
Published: (2021-08-01)

MZ1 co-operates with trastuzumab in HER2 positive breast cancer
by: María del Mar Noblejas-López, et al.
Published: (2021-03-01)

HER2 expression, copy number variation and survival outcomes in HER2-low non-metastatic breast cancer: an international multicentre cohort study and TCGA-METABRIC analysis
by: Ryan Shea Ying Cong Tan, et al.
Published: (2022-03-01)

The role of autophagy in HER2-targeted therapy
by: Félice A. Janser, et al.
Published: (2019-10-01)

Clinical and prognostic profile of Her2neu positive (non-luminal) intrinsic breast cancer subtype: comparison with Her2neu positive luminal breast cancers
by: Atif Ali Hashmi, et al.
Published: (2018-08-01)

Prognostic impact of HER2 biomarker levels in trastuzumab-treated early HER2-positive breast cancer
by: Caroline Rönnlund, et al.
Published: (2024-02-01)

Diagnostic value of serum HER2 levels in breast cancer: a systematic review and meta-analysis
by: Amir Shamshirian, et al.
Published: (2020-10-01)

HER2-Low Breast Cancer: Current Landscape and Future Prospects
by: Shirman Y, et al.
Published: (2023-08-01)

The Study of HER-2/neu, ER/PR Expression Using Immunohistochemistry (IHC) in the Iraqi Breast Cancer
by: Suhad Faisal Hatem, et al.
Published: (2016-06-01)

HER2-Targeted Tyrosine Kinase Inhibitors Cause Therapy-Induced-Senescence in Breast Cancer Cells
by: Martina S. J. McDermott, et al.
Published: (2019-02-01)

Case Report: Effective Treatment With Pyrotinib and Capecitabine in a Heavily Pretreated Locally Advanced Breast Cancer Harboring Both HER2 Overexpression and Mutant
by: Zhichao Gao, et al.
Published: (2021-10-01)

Progression-Free Survival and Overall Survival in Patients with Advanced HER2-Positive Breast Cancer Treated with Trastuzumab Emtansine (T-DM1) after Previous Treatment with Pertuzumab
by: Laura L. Michel, et al.
Published: (2020-10-01)

HER2 in Breast Cancer Stemness: A Negative Feedback Loop towards Trastuzumab Resistance
by: Babak Nami, et al.
Published: (2017-04-01)

Carbonic anhydrases reduce the acidity of the tumor microenvironment, promote immune infiltration, decelerate tumor growth, and improve survival in ErbB2/HER2-enriched breast cancer
by: Soojung Lee, et al.
Published: (2023-04-01)

Predictability of the Expression of ER, PR Receptors, HER2 and AgNORs in Breast Carcinoma among Iraqi Women in Thi - Qar Province: Immunohistochemical study
by: Hayfaa Abid Ali, et al.
Published: (2019-04-01)

Predictability of the Expression of ER, PR Receptors, HER2 and AgNORs in Breast Carcinoma among Iraqi Women in Thi - Qar Province: Immunohistochemical study
by: Hayfaa Abid Ali, et al.
Published: (2019-04-01)

Predictability of the Expression of ER, PR Receptors, HER2 and AgNORs in Breast Carcinoma among Iraqi Women in Thi - Qar Province: Immunohistochemical study
by: Hayfaa Abid Ali, et al.
Published: (2019-04-01)

Trastuzumab: updated mechanisms of action and resistance in breast cancer
by: Francois X. Claret, et al.
Published: (2012-06-01)

Conversion of ER, PR, HER2 and Ki-67 and Prognosis in breast cancer metastases to the brain
by: Chen Jiaxin, et al.
Published: (2022-10-01)

HER2 Aberrations in Non-Small Cell Lung Cancer: From Pathophysiology to Targeted Therapy
by: Ioannis A. Vathiotis, et al.
Published: (2021-12-01)

Challenges and future of HER2-positive gastric cancer therapy
by: Chenzhe Ma, et al.
Published: (2023-01-01)

Precision Medicine in Metastatic Colorectal Cancer: Targeting ERBB2 (HER-2) Oncogene
by: Javier Torres-Jiménez, et al.
Published: (2022-07-01)

Expression of HER2/c-erbB-2, EGFR protein in gastric carcinoma and its clinical significance
by: Cheng Guoxiong, et al.
Published: (2019-05-01)

Leptin and leptin receptor expression in breast carcinomas and their relationship with clinicopathological features
by: Irem Atalay Karacay, et al.
Published: (2022-11-01)

Upregulated Expression of ERBB2/HER2 in Multiple Myeloma as a Predictor of Poor Survival Outcomes
by: Fatih M. Uckun, et al.
Published: (2023-06-01)

Targeting Cell Cycle Progression in HER2+ Breast Cancer: An Emerging Treatment Opportunity
by: Nischal Koirala, et al.
Published: (2022-06-01)

Correlation between resistance to trastuzumab and miR-141 relative expression in the BT-474 human breast cancer cell line
by: Zohreh Rezaei, et al.
Published: (2017-10-01)

Frequency of HER-2 over Expression in the Patients with Breast Cancer after Mastectomy
by: S kargar, et al.
Published: (2013-10-01)

Novel HER2-Directed Treatments in Advanced Gastric Carcinoma: AnotHER Paradigm Shift?
by: Angela Dalia Ricci, et al.
Published: (2021-04-01)

Breast Cancer Subtypes among Iraqi Patients: Identified By Their ER, PR and HER2 Status
by: Nada A.S. Alwan, et al.
Published: (2018-01-01)

Murine Dendritic Cells Grown in Serum-Free Culture Show Potent Therapeutic Activity when Loaded with Novel Th Epitopes in an Orthotopic Model of HER2<sup>pos</sup> Breast Cancer
by: Loral E. Showalter, et al.
Published: (2021-09-01)

Estudo comparativo entre os métodos LSAB®+ e Herceptest® para a detecção de HER-2/neu em carcinoma de mama A comparative study between LSAB®+ and Herceptest® in the detection of HER-2/neu in breast carcinoma
by: Alexandre de Oliveira Sales, et al.
Published: (2004-08-01)

Human Blood Serum Inhibits Ductal Carcinoma Cells BT474 Growth and Modulates Effect of HER2 Inhibition
by: Dmitrii Kamashev, et al.
Published: (2022-08-01)

Trastuzumab-induced upregulation of a protein set in extracellular vesicles emitted by ErbB2-positive breast cancer cells correlates with their trastuzumab sensitivity
by: Arik Durcker, et al.
Published: (2020-10-01)

Predictive value of her-2 in breast cancer: Chemotherapy
by: Stamatović Ljiljana, et al.
Published: (2002-01-01)

Leptin and leptin receptor expression as biomarkers for breast cancer: a retrospective study
by: Yan Wang, et al.
Published: (2023-03-01)

Evaluation of the Prevalence of HER-2 Expression and Its Relationship with Prognostic Parameters in Colorectal Carcinoma
by: Cansu Benli Işık, et al.
Published: (2020-05-01)

Biomarker and multigene assay testing in ER positive, HER-2 negative breast carcinomas: An international guidelines-based approach
by: Bradley M. Turner, et al.
Published: (2021-11-01)

Correlation of HER-2/neu Status with Estrogen (ER) & Progesterone (PR) Receptor in Breast Malignancies
by: Asma Rasheed, et al.
Published: (2020-12-01)

NRG1/ERBB3/ERBB2 Axis Triggers Anchorage-Independent Growth of Basal-like/Triple-Negative Breast Cancer Cells
by: Carmen Miano, et al.
Published: (2022-03-01)