Role of gammadelta T cells in protecting normal airway function
<p>Abstract</p> <p>Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain no...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2000-11-01
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| Series: | Respiratory Research |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1186/rr26 |
| _version_ | 1811318000413835264 |
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| author | Gelfand Erwin W O'Brien Rebecca L Kanehiro Arihiko Takeda Katsuyuki Lahn Michael Born Willi K |
| author_facet | Gelfand Erwin W O'Brien Rebecca L Kanehiro Arihiko Takeda Katsuyuki Lahn Michael Born Willi K |
| author_sort | Gelfand Erwin W |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.</p> |
| first_indexed | 2024-04-13T12:18:11Z |
| format | Article |
| id | doaj.art-43903b89149b41749143ec9b5aa4af7b |
| institution | Directory Open Access Journal |
| issn | 1465-9921 |
| language | English |
| last_indexed | 2024-04-13T12:18:11Z |
| publishDate | 2000-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-43903b89149b41749143ec9b5aa4af7b2022-12-22T02:47:18ZengBMCRespiratory Research1465-99212000-11-011315115810.1186/rr26Role of gammadelta T cells in protecting normal airway functionGelfand Erwin WO'Brien Rebecca LKanehiro ArihikoTakeda KatsuyukiLahn MichaelBorn Willi K<p>Abstract</p> <p>Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.</p>http://dx.doi.org/10.1186/rr26γδ T cellsasthmaairway hyper-responsivenesslymphocytes |
| spellingShingle | Gelfand Erwin W O'Brien Rebecca L Kanehiro Arihiko Takeda Katsuyuki Lahn Michael Born Willi K Role of gammadelta T cells in protecting normal airway function Respiratory Research γδ T cells asthma airway hyper-responsiveness lymphocytes |
| title | Role of gammadelta T cells in protecting normal airway function |
| title_full | Role of gammadelta T cells in protecting normal airway function |
| title_fullStr | Role of gammadelta T cells in protecting normal airway function |
| title_full_unstemmed | Role of gammadelta T cells in protecting normal airway function |
| title_short | Role of gammadelta T cells in protecting normal airway function |
| title_sort | role of gammadelta t cells in protecting normal airway function |
| topic | γδ T cells asthma airway hyper-responsiveness lymphocytes |
| url | http://dx.doi.org/10.1186/rr26 |
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