Role of gammadelta T cells in protecting normal airway function
<p>Abstract</p> <p>Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain no...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
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BMC
2000-11-01
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Series: | Respiratory Research |
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Online Access: | http://dx.doi.org/10.1186/rr26 |
_version_ | 1811318000413835264 |
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author | Gelfand Erwin W O'Brien Rebecca L Kanehiro Arihiko Takeda Katsuyuki Lahn Michael Born Willi K |
author_facet | Gelfand Erwin W O'Brien Rebecca L Kanehiro Arihiko Takeda Katsuyuki Lahn Michael Born Willi K |
author_sort | Gelfand Erwin W |
collection | DOAJ |
description | <p>Abstract</p> <p>Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.</p> |
first_indexed | 2024-04-13T12:18:11Z |
format | Article |
id | doaj.art-43903b89149b41749143ec9b5aa4af7b |
institution | Directory Open Access Journal |
issn | 1465-9921 |
language | English |
last_indexed | 2024-04-13T12:18:11Z |
publishDate | 2000-11-01 |
publisher | BMC |
record_format | Article |
series | Respiratory Research |
spelling | doaj.art-43903b89149b41749143ec9b5aa4af7b2022-12-22T02:47:18ZengBMCRespiratory Research1465-99212000-11-011315115810.1186/rr26Role of gammadelta T cells in protecting normal airway functionGelfand Erwin WO'Brien Rebecca LKanehiro ArihikoTakeda KatsuyukiLahn MichaelBorn Willi K<p>Abstract</p> <p>Since their discovery 15 years ago, the role of γδ T cells has remained somewhat elusive. Responses of γδ T cells have been found in numerous infectious and non-infectious diseases. New evidence points to γδ T cells' functioning in the airways to maintain normal airway responsiveness or tone. In the lung, distinct subsets of γδ T cell subsets seem to have specific roles, one subset promoting allergic inflammation, the other serving a protective role.</p>http://dx.doi.org/10.1186/rr26γδ T cellsasthmaairway hyper-responsivenesslymphocytes |
spellingShingle | Gelfand Erwin W O'Brien Rebecca L Kanehiro Arihiko Takeda Katsuyuki Lahn Michael Born Willi K Role of gammadelta T cells in protecting normal airway function Respiratory Research γδ T cells asthma airway hyper-responsiveness lymphocytes |
title | Role of gammadelta T cells in protecting normal airway function |
title_full | Role of gammadelta T cells in protecting normal airway function |
title_fullStr | Role of gammadelta T cells in protecting normal airway function |
title_full_unstemmed | Role of gammadelta T cells in protecting normal airway function |
title_short | Role of gammadelta T cells in protecting normal airway function |
title_sort | role of gammadelta t cells in protecting normal airway function |
topic | γδ T cells asthma airway hyper-responsiveness lymphocytes |
url | http://dx.doi.org/10.1186/rr26 |
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