Traditional Chinese medicine based on Tongjiang methodology combined with proton pump inhibitor (PPI) step-down in treating non-erosive reflux disease: a study protocol for a multicentered, randomized controlled clinical trial

Traditional Chinese medicine based on Tongjiang methodology combined with proton pump inhibitor (PPI) step-down in treating non-erosive reflux disease: a study protocol for a multicentered, randomized controlled clinical trial

Abstract Background Non-erosive reflux disease (NERD) is characterized by typical gastroesophageal reflux symptoms, such as heartburn and regurgitation but an absence of esophageal mucosal damage during upper gastrointestinal endoscopy. Although proton pump inhibitors (PPIs) are the first line thera...

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Bibliographic Details
Main Authors: Xia Li, Haomeng Wu, Beihua Zhang, Ting Chen, Xiaoshuang Shi, Jinxin Ma, Jiaqi Zhang, Xudong Tang, Fengyun Wang
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Trials
Subjects:
Nonerosive reflux disease (NERD)
TCM granules
PPI
Randomized controlled trial (RCT)
Protocol
Online Access:https://doi.org/10.1186/s13063-022-06811-x

Internet

https://doi.org/10.1186/s13063-022-06811-x

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