Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II

Background: Lead is one of the heavy metals that is persists in the environment and has destructive effects on various human tissues. We investigated the effects of lead on the histological features of liver and its enzymatic functions. Methods: Forty chickens were purchased and randomly divided i...

Full description

Bibliographic Details
Main Authors: Milad Ashrafizadeh*, Hossein Rafiei, Zahra Ahmadi
Format: Article
Language:English
Published: Arak University of Medical Sciences 2018-11-01
Series:Iranian Journal of Toxicology
Subjects:
Online Access:http://ijt.arakmu.ac.ir/article-1-703-en.pdf
_version_ 1818835132343123968
author Milad Ashrafizadeh*
Hossein Rafiei
Zahra Ahmadi
author_facet Milad Ashrafizadeh*
Hossein Rafiei
Zahra Ahmadi
author_sort Milad Ashrafizadeh*
collection DOAJ
description Background: Lead is one of the heavy metals that is persists in the environment and has destructive effects on various human tissues. We investigated the effects of lead on the histological features of liver and its enzymatic functions. Methods: Forty chickens were purchased and randomly divided into four groups. In addition to the normal feed, each group received different doses of lead acetate II in the feed. After preparing microscopic slides, the level of liver enzymes was measured. Results: It was demonstrated that the level of liver enzymes increases and devastating effects on the liver structures occurred. Conclusion: In according to the adverse effects of lead on the liver and due to the increase use of this harmful agent in the different parts and its increase in the air, especially in Iran, there is a need for considering a comprehensive plan for preventing of more outbreak of this agents and inhibiting the toxic effects of it on the birds.
first_indexed 2024-12-19T02:45:51Z
format Article
id doaj.art-43949d0bcbec4485b45a1246e2aae766
institution Directory Open Access Journal
issn 2008-2967
2251-9459
language English
last_indexed 2024-12-19T02:45:51Z
publishDate 2018-11-01
publisher Arak University of Medical Sciences
record_format Article
series Iranian Journal of Toxicology
spelling doaj.art-43949d0bcbec4485b45a1246e2aae7662022-12-21T20:38:53ZengArak University of Medical SciencesIranian Journal of Toxicology2008-29672251-94592018-11-0112615Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate IIMilad Ashrafizadeh* 0Hossein Rafiei 1 Zahra Ahmadi 2Department of Basic Science, Veterinary Medicine Faculty, Tabriz University, Tabriz, Iran. * Corresponding Author: E-mail: dvm.milad73@yahoo.comDepartment of Biology, Faculty of Sciences, Islamic Azad University, Shiraz, IranDepartment of Basic Science, Veterinary Medicine Faculty, Shushtar University, Khuzestan, Iran.Background: Lead is one of the heavy metals that is persists in the environment and has destructive effects on various human tissues. We investigated the effects of lead on the histological features of liver and its enzymatic functions. Methods: Forty chickens were purchased and randomly divided into four groups. In addition to the normal feed, each group received different doses of lead acetate II in the feed. After preparing microscopic slides, the level of liver enzymes was measured. Results: It was demonstrated that the level of liver enzymes increases and devastating effects on the liver structures occurred. Conclusion: In according to the adverse effects of lead on the liver and due to the increase use of this harmful agent in the different parts and its increase in the air, especially in Iran, there is a need for considering a comprehensive plan for preventing of more outbreak of this agents and inhibiting the toxic effects of it on the birds.http://ijt.arakmu.ac.ir/article-1-703-en.pdfBiochemical ParametersChickenLeadLiver
spellingShingle Milad Ashrafizadeh*
Hossein Rafiei
Zahra Ahmadi
Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II
Iranian Journal of Toxicology
Biochemical Parameters
Chicken
Lead
Liver
title Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II
title_full Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II
title_fullStr Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II
title_full_unstemmed Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II
title_short Histological Changes in the Liver and Biochemical Parameters of Chickens Treated with Lead Acetate II
title_sort histological changes in the liver and biochemical parameters of chickens treated with lead acetate ii
topic Biochemical Parameters
Chicken
Lead
Liver
url http://ijt.arakmu.ac.ir/article-1-703-en.pdf
work_keys_str_mv AT miladashrafizadeh histologicalchangesintheliverandbiochemicalparametersofchickenstreatedwithleadacetateii
AT hosseinrafiei histologicalchangesintheliverandbiochemicalparametersofchickenstreatedwithleadacetateii
AT zahraahmadi histologicalchangesintheliverandbiochemicalparametersofchickenstreatedwithleadacetateii