Expansion of hematopoietic stem cells for transplantation: current perspectives

Expansion of hematopoietic stem cells for transplantation: current perspectives

<p>Abstract</p> <p>Hematopoietic stem cells (HSCs) are rare cells that have the unique ability to self-renew and differentiate into cells of all hematopoietic lineages. The expansion of HSCs has remained an important goal to develop advanced cell therapies for bone marrow transplan...

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Bibliographic Details
Main Authors: Schuster Jessica A, Stupnikov Maria R, Ma Gina, Liao Wenbin, Lai Raymond, Ma Yupo, Aguila Jerell R
Format: Article
Language:English
Published: BMC 2012-05-01
Series:Experimental Hematology & Oncology
Subjects:
Stem cell expansion
Gene therapy
Epigenetics
Umbilical cord blood
HOXB4
SALL4
Notch signaling
Online Access:http://www.ehoonline.org/content/1/1/12

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