Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila

Sleep homeostasis regulated by 5HT2b receptor in a small subset of neurons in the dorsal fan-shaped body of drosophila

Our understanding of the molecular mechanisms underlying sleep homeostasis is limited. We have taken a systematic approach to study neural signaling by the transmitter 5-hydroxytryptamine (5-HT) in drosophila. We have generated knockout and knockin lines for Trh, the 5-HT synthesizing enzyme and all...

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Bibliographic Details
Main Authors: Yongjun Qian, Yue Cao, Bowen Deng, Guang Yang, Jiayun Li, Rui Xu, Dandan zhang, Juan Huang, Yi Rao
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
sleep homeostasis
serotonin
5HT2b receptor
dFB neurons
Online Access:https://elifesciences.org/articles/26519

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