KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2

KLF8 Promotes the Survival of Lung Adenocarcinoma During Nutrient Deprivation by Regulating the Pentose Phosphate Pathway through SIRT2

Background: The pentose phosphate pathway (PPP) is a critical metabolic pathway that generates NADPH and ribose-5-phosphate for nucleotide biosynthesis and redox homeostasis. In this study, we investigated a potential regulatory role for Krüppel-like factor 8 (KLF8) in the control of PPP in lung ade...

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Bibliographic Details
Main Authors: Qiaohong Bai, Wenfang Jin, Futao Chen, Jiang Zhu, Lifeng Cao, Yang Yang, Fukuan Zhong, Li Li
Format: Article
Language:English
Published: IMR Press 2024-01-01
Series:Frontiers in Bioscience-Landmark
Subjects:
pentose phosphate pathway
nutrient deprivation
klf8
tumor metabolism
Online Access:https://www.imrpress.com/journal/FBL/29/1/10.31083/j.fbl2901027

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