Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients

Peritoneal Protein Clearance Is a Function of Local Inflammation and Membrane Area Whereas Systemic Inflammation and Comorbidity Predict Survival of Incident Peritoneal Dialysis Patients

It is not clear whether the association of increased peritoneal protein clearance (PPCl) with worse survival on peritoneal dialysis (PD) is a consequence of either local or systemic inflammation or indicative of generalized endothelial dysfunction associated with comorbidity. To investigate this we...

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Bibliographic Details
Main Authors: Zanzhe Yu, Mark Lambie, James Chess, Andrew Williams, Jun-Young Do, Nicholas Topley, Simon J. Davies
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
large pore flux
survival
mortality
hypoalbuminaemia
interleukin-6
peritoneal solute transport rate
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00105/full

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