Cepharanthine and Oral Lichen Planus Efficacy (COLE) study: protocol for a multicentre randomised controlled study assessing the efficacy and safety of cepharanthine with topical corticosteroids in oral lichen planus
Introduction Oral lichen planus (OLP) is a chronic, inflammatory oral condition leading to a range of symptoms from mild discomfort to severe pain, affecting patients’ quality of life. Standard therapy involves the use of topical corticosteroids, although some patients respond insufficiently or deve...
Main Authors: | Kazuhiko Yamamoto, Takahiro Yagyuu, Yumiko Matsusue, Tadaaki Kirita, Masato Kasahara, Masahiro Isogawa, Tsutomu Sugiura |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2023-08-01
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Series: | BMJ Open |
Online Access: | https://bmjopen.bmj.com/content/13/8/e074279.full |
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