Are fetal and early neonatal period defining our life destiny?

Children born small for gestational age (SGA) are classified as instants whose birth weight and/or birth length deviates more than 2 SD below the average for gestational age. They are at high risk of developing serious metabolic disorders by the process of foetal and early neonatal programming. Any...

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Main Authors: Živić Saša, Manojlović Milena, Stanković Sandra, Vučić Jelena, Milojević Dejan, Vasić Karin, Cvetković Vesna
Format: Article
Language:English
Published: Specijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma Zlatibor 2018-01-01
Series:Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"
Subjects:
Online Access:https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2018/1821-19251869030Z.pdf
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author Živić Saša
Manojlović Milena
Stanković Sandra
Vučić Jelena
Milojević Dejan
Vasić Karin
Cvetković Vesna
author_facet Živić Saša
Manojlović Milena
Stanković Sandra
Vučić Jelena
Milojević Dejan
Vasić Karin
Cvetković Vesna
author_sort Živić Saša
collection DOAJ
description Children born small for gestational age (SGA) are classified as instants whose birth weight and/or birth length deviates more than 2 SD below the average for gestational age. They are at high risk of developing serious metabolic disorders by the process of foetal and early neonatal programming. Any structural or functional changes that occur in this way are generally irreversible. As a result, sudden addition in body weight is enabling early constitution of the metabolic syndrome with all its consequences, including high early cardiovascular and cerebrovascular morbidity and mortality as well as other organ systems disturbances. About 65,000 children are born annually in Serbia. According to a respectable database of children treated with growth hormone, during period of 9 years were born about 590,000 children and about 10% of them were SGA (59,000 of them). 10% i.e. 5,900 of them should receive a growth hormone. However, only 260 children who receive growth hormone are in the database (only 4% of them are detected). More tragically - none of SGA children with rapid postnatal growth, programmed for adult illness, has been recognized until this day!.
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publishDate 2018-01-01
publisher Specijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma Zlatibor
record_format Article
series Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"
spelling doaj.art-43ad28b236e142e5b79dd8a6a5f842f62022-12-22T03:51:40ZengSpecijalna bolnica za bolesti štitaste žlezde i bolesti metabolizma ZlatiborMedicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"1821-19252406-131X2018-01-01236930421821-19251869030ZAre fetal and early neonatal period defining our life destiny?Živić Saša0Manojlović Milena1Stanković Sandra2Vučić Jelena3Milojević Dejan4Vasić Karin5Cvetković Vesna6Klinika za dečije interne bolesti, klinički centar, Niš + Univerzitet u Nišu, Medicinski fakultetUniverzitet u Nišu, Medicinski fakultetKlinički centar, Klinika za dečije interne bolesti, NišKlinički centar, Klinika za dečije interne bolesti, NišKlinički centar, Klinika za dečije interne bolesti, NišKlinički centar, Klinika za dečije interne bolesti, NišKlinički centar, Klinika za dečije interne bolesti, NišChildren born small for gestational age (SGA) are classified as instants whose birth weight and/or birth length deviates more than 2 SD below the average for gestational age. They are at high risk of developing serious metabolic disorders by the process of foetal and early neonatal programming. Any structural or functional changes that occur in this way are generally irreversible. As a result, sudden addition in body weight is enabling early constitution of the metabolic syndrome with all its consequences, including high early cardiovascular and cerebrovascular morbidity and mortality as well as other organ systems disturbances. About 65,000 children are born annually in Serbia. According to a respectable database of children treated with growth hormone, during period of 9 years were born about 590,000 children and about 10% of them were SGA (59,000 of them). 10% i.e. 5,900 of them should receive a growth hormone. However, only 260 children who receive growth hormone are in the database (only 4% of them are detected). More tragically - none of SGA children with rapid postnatal growth, programmed for adult illness, has been recognized until this day!.https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2018/1821-19251869030Z.pdfsmall for gestational age (SGA)fetal programmingmetabolic syndrome
spellingShingle Živić Saša
Manojlović Milena
Stanković Sandra
Vučić Jelena
Milojević Dejan
Vasić Karin
Cvetković Vesna
Are fetal and early neonatal period defining our life destiny?
Medicinski Glasnik Specijalne Bolnice za Bolesti Štitaste Žlezde i Bolesti Metabolizma "Zlatibor"
small for gestational age (SGA)
fetal programming
metabolic syndrome
title Are fetal and early neonatal period defining our life destiny?
title_full Are fetal and early neonatal period defining our life destiny?
title_fullStr Are fetal and early neonatal period defining our life destiny?
title_full_unstemmed Are fetal and early neonatal period defining our life destiny?
title_short Are fetal and early neonatal period defining our life destiny?
title_sort are fetal and early neonatal period defining our life destiny
topic small for gestational age (SGA)
fetal programming
metabolic syndrome
url https://scindeks-clanci.ceon.rs/data/pdf/1821-1925/2018/1821-19251869030Z.pdf
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