Early developmental phenotypes in the cystic fibrosis sheep model

Early developmental phenotypes in the cystic fibrosis sheep model

Abstract Highly effective modulator therapies for cystic fibrosis (CF) make it a treatable condition for many people. However, although CF respiratory illness occurs after birth, other organ systems particularly in the digestive tract are damaged before birth. We use an ovine model of CF to investig...

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Bibliographic Details
Main Authors: Arnaud J. Van Wettere, Shih‐Hsing Leir, Calvin U. Cotton, Misha Regouski, Iuri Viotti Perisse, Jenny L. Kerschner, Alekh Paranjapye, Zhiqiang Fan, Ying Liu, Makayla Schacht, Kenneth L. White, Irina A. Polejaeva, Ann Harris
Format: Article
Language:English
Published: Wiley 2023-01-01
Series:FASEB BioAdvances
Subjects:
CF development
CFTR
CF GI tract
CF liver
CF lung
CF pancreas
Online Access:https://doi.org/10.1096/fba.2022-00085

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