Sputum microbiome α-diversity is a key feature of the COPD frequent exacerbator phenotype

Sputum microbiome α-diversity is a key feature of the COPD frequent exacerbator phenotype

Background The lung microbiome is an inflammatory stimulus whose role in COPD pathogenesis is incompletely understood. We hypothesised that the frequent exacerbator phenotype is associated with decreased α-diversity and increased lung inflammation. Our objective was to assess correlations between th...

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Bibliographic Details
Main Authors: Alexa A. Pragman, Shane W. Hodgson, Tianhua Wu, Allison Zank, Cavan S. Reilly, Chris H. Wendt
Format: Article
Language:English
Published: European Respiratory Society 2024-02-01
Series:ERJ Open Research
Online Access:http://openres.ersjournals.com/content/10/1/00595-2023.full

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