Dihydrotestosterone induces SREBP-1 expression and lipogenesis through the phosphoinositide 3-kinase/Akt pathway in HaCaT cells

Dihydrotestosterone induces SREBP-1 expression and lipogenesis through the phosphoinositide 3-kinase/Akt pathway in HaCaT cells

<p>Abstract</p> <p>Background</p> <p>The purpose of this study was to investigate the effects and mechanisms of dihydrotestosterone (DHT)-induced expression of sterol regulatory element binding protein-1 (SREBP-1), and the synthesis and secretion of lipids, in HaCaT cel...

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Bibliographic Details
Main Authors: Zhou Bing-rong, Huang Qiu-hong, Xu Yang, Wu Di, Yin Zhi-qiang, Luo Dan
Format: Article
Language:English
Published: BMC 2012-11-01
Series:Lipids in Health and Disease
Subjects:
Dihydrotestosterone
SREBP-1
Phosphoinositide 3-kinase/Akt
HaCaT cells
Online Access:http://www.lipidworld.com/content/11/1/156

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