Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes

Regulation of Human Sortilin Alternative Splicing by Glucagon-like Peptide-1 (GLP1) in Adipocytes

Type 2 diabetes mellitus is a chronic metabolic disease with no cure. Adipose tissue is a major site of systemic insulin resistance. Sortilin is a central component of the glucose transporter -Glut4 storage vesicles (GSV) which translocate to the plasma membrane to uptake glucose from circulation. H...

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Bibliographic Details
Main Authors:	Ashley Lui, Rekha S. Patel, Meredith Krause-Hauch, Robert P. Sparks, Niketa A. Patel
Format:	Article
Language:	English
Published:	MDPI AG 2023-09-01
Series:	International Journal of Molecular Sciences
Subjects:	type 2 diabetes human adipocytes human adipose tissue glucose uptake splicing minigene antisense oligonucleotides
Online Access:	https://www.mdpi.com/1422-0067/24/18/14324

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