Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]

Background: People with tuberculosis disease and their household members may suffer direct out-of-pocket expenses and indirect costs of lost income. These tuberculosis-related costs can worsen poverty, make tuberculosis treatment completion unaffordable, impair quality of life and increase the risk...

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Main Authors: Sumona Datta, Paula P. Carballo-Jimenez, Matthew J. Saunders, Rubén Aguirre-Ipenza, Carlton A. Evans, Luz Quevedo Cruz
Format: Article
Language:English
Published: Wellcome 2022-11-01
Series:Wellcome Open Research
Subjects:
Online Access:https://wellcomeopenresearch.org/articles/7-92/v2
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author Sumona Datta
Paula P. Carballo-Jimenez
Matthew J. Saunders
Rubén Aguirre-Ipenza
Carlton A. Evans
Luz Quevedo Cruz
author_facet Sumona Datta
Paula P. Carballo-Jimenez
Matthew J. Saunders
Rubén Aguirre-Ipenza
Carlton A. Evans
Luz Quevedo Cruz
author_sort Sumona Datta
collection DOAJ
description Background: People with tuberculosis disease and their household members may suffer direct out-of-pocket expenses and indirect costs of lost income. These tuberculosis-related costs can worsen poverty, make tuberculosis treatment completion unaffordable, impair quality of life and increase the risk of death. Costs due to tuberculosis are usually defined as catastrophic if they exceed 20% of the pre-disease annual household income. The World Health Organisation strategy to “End TB” and the United Nations Sustainable Development Goals include the target that no households should face catastrophic costs due to tuberculosis. However, there is limited evidence and policy concerning how this global priority of eliminating catastrophic costs due to tuberculosis should be achieved. This systematic review and meta-analysis aims to address this knowledge gap. Methods: Publications assessing interventions that aimed to eliminate catastrophic costs will be identified by searching three electronic databases (PubMed, Scopus and Web of Science) together with reference lists from pertinent publications. We will screen eligible studies, extract data, and assess the risk of bias with the quality assessment tool from the National Heart, Lung, and Blood Institute. Discrepancies will be resolved by discussion between the reviewers. If we find sufficient comparable studies quantifying strategies to eliminate catastrophic costs then a meta-analysis will be performed. This systematic review and meta-analysis is registered with the PROSPERO database (CRD42022292410). Conclusion: This systematic review and meta-analysis aims to rigorously assess the evidence for strategies to eliminate catastrophic costs due to tuberculosis.
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spelling doaj.art-43cc82269384457bb20e4c1200bb68ea2023-05-10T01:00:00ZengWellcomeWellcome Open Research2398-502X2022-11-01720392Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]Sumona Datta0https://orcid.org/0000-0002-3476-9753Paula P. Carballo-Jimenez1https://orcid.org/0000-0003-3196-4075Matthew J. Saunders2Rubén Aguirre-Ipenza3https://orcid.org/0000-0001-9853-0824Carlton A. Evans4https://orcid.org/0000-0002-6873-5447Luz Quevedo Cruz5https://orcid.org/0000-0002-7463-3965IFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKUniversidad Continental, Lima, PeruIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKBackground: People with tuberculosis disease and their household members may suffer direct out-of-pocket expenses and indirect costs of lost income. These tuberculosis-related costs can worsen poverty, make tuberculosis treatment completion unaffordable, impair quality of life and increase the risk of death. Costs due to tuberculosis are usually defined as catastrophic if they exceed 20% of the pre-disease annual household income. The World Health Organisation strategy to “End TB” and the United Nations Sustainable Development Goals include the target that no households should face catastrophic costs due to tuberculosis. However, there is limited evidence and policy concerning how this global priority of eliminating catastrophic costs due to tuberculosis should be achieved. This systematic review and meta-analysis aims to address this knowledge gap. Methods: Publications assessing interventions that aimed to eliminate catastrophic costs will be identified by searching three electronic databases (PubMed, Scopus and Web of Science) together with reference lists from pertinent publications. We will screen eligible studies, extract data, and assess the risk of bias with the quality assessment tool from the National Heart, Lung, and Blood Institute. Discrepancies will be resolved by discussion between the reviewers. If we find sufficient comparable studies quantifying strategies to eliminate catastrophic costs then a meta-analysis will be performed. This systematic review and meta-analysis is registered with the PROSPERO database (CRD42022292410). Conclusion: This systematic review and meta-analysis aims to rigorously assess the evidence for strategies to eliminate catastrophic costs due to tuberculosis.https://wellcomeopenresearch.org/articles/7-92/v2systematic review meta-analysis catastrophic costs tuberculosiseng
spellingShingle Sumona Datta
Paula P. Carballo-Jimenez
Matthew J. Saunders
Rubén Aguirre-Ipenza
Carlton A. Evans
Luz Quevedo Cruz
Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]
Wellcome Open Research
systematic review
meta-analysis
catastrophic costs
tuberculosis
eng
title Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]
title_full Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]
title_fullStr Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]
title_full_unstemmed Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]
title_short Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]
title_sort interventions aiming to eliminate catastrophic costs due to tuberculosis a protocol for a systematic review and meta analysis version 2 peer review 2 approved
topic systematic review
meta-analysis
catastrophic costs
tuberculosis
eng
url https://wellcomeopenresearch.org/articles/7-92/v2
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