Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]
Background: People with tuberculosis disease and their household members may suffer direct out-of-pocket expenses and indirect costs of lost income. These tuberculosis-related costs can worsen poverty, make tuberculosis treatment completion unaffordable, impair quality of life and increase the risk...
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Wellcome
2022-11-01
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Series: | Wellcome Open Research |
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Online Access: | https://wellcomeopenresearch.org/articles/7-92/v2 |
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author | Sumona Datta Paula P. Carballo-Jimenez Matthew J. Saunders Rubén Aguirre-Ipenza Carlton A. Evans Luz Quevedo Cruz |
author_facet | Sumona Datta Paula P. Carballo-Jimenez Matthew J. Saunders Rubén Aguirre-Ipenza Carlton A. Evans Luz Quevedo Cruz |
author_sort | Sumona Datta |
collection | DOAJ |
description | Background: People with tuberculosis disease and their household members may suffer direct out-of-pocket expenses and indirect costs of lost income. These tuberculosis-related costs can worsen poverty, make tuberculosis treatment completion unaffordable, impair quality of life and increase the risk of death. Costs due to tuberculosis are usually defined as catastrophic if they exceed 20% of the pre-disease annual household income. The World Health Organisation strategy to “End TB” and the United Nations Sustainable Development Goals include the target that no households should face catastrophic costs due to tuberculosis. However, there is limited evidence and policy concerning how this global priority of eliminating catastrophic costs due to tuberculosis should be achieved. This systematic review and meta-analysis aims to address this knowledge gap. Methods: Publications assessing interventions that aimed to eliminate catastrophic costs will be identified by searching three electronic databases (PubMed, Scopus and Web of Science) together with reference lists from pertinent publications. We will screen eligible studies, extract data, and assess the risk of bias with the quality assessment tool from the National Heart, Lung, and Blood Institute. Discrepancies will be resolved by discussion between the reviewers. If we find sufficient comparable studies quantifying strategies to eliminate catastrophic costs then a meta-analysis will be performed. This systematic review and meta-analysis is registered with the PROSPERO database (CRD42022292410). Conclusion: This systematic review and meta-analysis aims to rigorously assess the evidence for strategies to eliminate catastrophic costs due to tuberculosis. |
first_indexed | 2024-04-09T13:31:40Z |
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institution | Directory Open Access Journal |
issn | 2398-502X |
language | English |
last_indexed | 2024-04-09T13:31:40Z |
publishDate | 2022-11-01 |
publisher | Wellcome |
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series | Wellcome Open Research |
spelling | doaj.art-43cc82269384457bb20e4c1200bb68ea2023-05-10T01:00:00ZengWellcomeWellcome Open Research2398-502X2022-11-01720392Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved]Sumona Datta0https://orcid.org/0000-0002-3476-9753Paula P. Carballo-Jimenez1https://orcid.org/0000-0003-3196-4075Matthew J. Saunders2Rubén Aguirre-Ipenza3https://orcid.org/0000-0001-9853-0824Carlton A. Evans4https://orcid.org/0000-0002-6873-5447Luz Quevedo Cruz5https://orcid.org/0000-0002-7463-3965IFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKUniversidad Continental, Lima, PeruIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKIFHAD: Innovation For Health And Development, Department of Infectious Disease, Imperial College London, London, UKBackground: People with tuberculosis disease and their household members may suffer direct out-of-pocket expenses and indirect costs of lost income. These tuberculosis-related costs can worsen poverty, make tuberculosis treatment completion unaffordable, impair quality of life and increase the risk of death. Costs due to tuberculosis are usually defined as catastrophic if they exceed 20% of the pre-disease annual household income. The World Health Organisation strategy to “End TB” and the United Nations Sustainable Development Goals include the target that no households should face catastrophic costs due to tuberculosis. However, there is limited evidence and policy concerning how this global priority of eliminating catastrophic costs due to tuberculosis should be achieved. This systematic review and meta-analysis aims to address this knowledge gap. Methods: Publications assessing interventions that aimed to eliminate catastrophic costs will be identified by searching three electronic databases (PubMed, Scopus and Web of Science) together with reference lists from pertinent publications. We will screen eligible studies, extract data, and assess the risk of bias with the quality assessment tool from the National Heart, Lung, and Blood Institute. Discrepancies will be resolved by discussion between the reviewers. If we find sufficient comparable studies quantifying strategies to eliminate catastrophic costs then a meta-analysis will be performed. This systematic review and meta-analysis is registered with the PROSPERO database (CRD42022292410). Conclusion: This systematic review and meta-analysis aims to rigorously assess the evidence for strategies to eliminate catastrophic costs due to tuberculosis.https://wellcomeopenresearch.org/articles/7-92/v2systematic review meta-analysis catastrophic costs tuberculosiseng |
spellingShingle | Sumona Datta Paula P. Carballo-Jimenez Matthew J. Saunders Rubén Aguirre-Ipenza Carlton A. Evans Luz Quevedo Cruz Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved] Wellcome Open Research systematic review meta-analysis catastrophic costs tuberculosis eng |
title | Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved] |
title_full | Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved] |
title_fullStr | Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved] |
title_full_unstemmed | Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved] |
title_short | Interventions aiming to eliminate catastrophic costs due to tuberculosis: a protocol for a systematic review and meta-analysis [version 2; peer review: 2 approved] |
title_sort | interventions aiming to eliminate catastrophic costs due to tuberculosis a protocol for a systematic review and meta analysis version 2 peer review 2 approved |
topic | systematic review meta-analysis catastrophic costs tuberculosis eng |
url | https://wellcomeopenresearch.org/articles/7-92/v2 |
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