Co‐delivery of cisplatin and oleanolic acid by silica nanoparticles‐enhanced apoptosis and reverse multidrug resistance in lung cancer

Co‐delivery of cisplatin and oleanolic acid by silica nanoparticles‐enhanced apoptosis and reverse multidrug resistance in lung cancer

Abstract Multidrug resistance (MDR) of chemotherapy is one of the significant concerns in cancer therapy. Here in our study, cisplatin (DDP) and oleanolic acid (OA) were co‐loaded in mesoporous silica nanoparticles (Nsi) to construct DDP/OA‐Nsi and solve the DDP‐resistance in lung cancer therapy. Th...

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Bibliographic Details
Main Authors: Xiao‐Kai Zhang, Qi‐Wen Wang, Ya‐Juan Xu, Hong‐Mei Sun, Lei Wang, Li‐Xin Zhang
Format: Article
Language:English
Published: Wiley 2021-06-01
Series:Kaohsiung Journal of Medical Sciences
Subjects:
cisplatin
lung cancer
oleanolic acid
silica nanoparticle
Online Access:https://doi.org/10.1002/kjm2.12365

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