Nanofiber Carriers of Therapeutic Load: Current Trends
The fast advancement in nanotechnology has prompted the improvement of numerous methods for the creation of various nanoscale composites of which nanofibers have gotten extensive consideration. Nanofibers are polymeric/composite fibers which have a nanoscale diameter. They vary in porous structure a...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-08-01
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| Series: | International Journal of Molecular Sciences |
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| Online Access: | https://www.mdpi.com/1422-0067/23/15/8581 |
| _version_ | 1797413580321062912 |
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| author | Ivana Jarak Inês Silva Cátia Domingues Ana Isabel Santos Francisco Veiga Ana Figueiras |
| author_facet | Ivana Jarak Inês Silva Cátia Domingues Ana Isabel Santos Francisco Veiga Ana Figueiras |
| author_sort | Ivana Jarak |
| collection | DOAJ |
| description | The fast advancement in nanotechnology has prompted the improvement of numerous methods for the creation of various nanoscale composites of which nanofibers have gotten extensive consideration. Nanofibers are polymeric/composite fibers which have a nanoscale diameter. They vary in porous structure and have an extensive area. Material choice is of crucial importance for the assembly of nanofibers and their function as efficient drug and biomedicine carriers. A broad scope of active pharmaceutical ingredients can be incorporated within the nanofibers or bound to their surface. The ability to deliver small molecular drugs such as antibiotics or anticancer medications, proteins, peptides, cells, DNA and RNAs has led to the biomedical application in disease therapy and tissue engineering. Although nanofibers have shown incredible potential for drug and biomedicine applications, there are still difficulties which should be resolved before they can be utilized in clinical practice. This review intends to give an outline of the recent advances in nanofibers, contemplating the preparation methods, the therapeutic loading and release and the various therapeutic applications. |
| first_indexed | 2024-03-09T05:21:03Z |
| format | Article |
| id | doaj.art-43cfd7e0a74f4624bc0b61bcc020167b |
| institution | Directory Open Access Journal |
| issn | 1661-6596 1422-0067 |
| language | English |
| last_indexed | 2024-03-09T05:21:03Z |
| publishDate | 2022-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | International Journal of Molecular Sciences |
| spelling | doaj.art-43cfd7e0a74f4624bc0b61bcc020167b2023-12-03T12:40:41ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672022-08-012315858110.3390/ijms23158581Nanofiber Carriers of Therapeutic Load: Current TrendsIvana Jarak0Inês Silva1Cátia Domingues2Ana Isabel Santos3Francisco Veiga4Ana Figueiras5Laboratory of Drug Development and Technologies, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, PortugalLaboratory of Drug Development and Technologies, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, PortugalLaboratory of Drug Development and Technologies, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, PortugalLaboratory of Drug Development and Technologies, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, PortugalLaboratory of Drug Development and Technologies, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, PortugalLaboratory of Drug Development and Technologies, Faculty of Pharmacy, University of Coimbra, 3000-548 Coimbra, PortugalThe fast advancement in nanotechnology has prompted the improvement of numerous methods for the creation of various nanoscale composites of which nanofibers have gotten extensive consideration. Nanofibers are polymeric/composite fibers which have a nanoscale diameter. They vary in porous structure and have an extensive area. Material choice is of crucial importance for the assembly of nanofibers and their function as efficient drug and biomedicine carriers. A broad scope of active pharmaceutical ingredients can be incorporated within the nanofibers or bound to their surface. The ability to deliver small molecular drugs such as antibiotics or anticancer medications, proteins, peptides, cells, DNA and RNAs has led to the biomedical application in disease therapy and tissue engineering. Although nanofibers have shown incredible potential for drug and biomedicine applications, there are still difficulties which should be resolved before they can be utilized in clinical practice. This review intends to give an outline of the recent advances in nanofibers, contemplating the preparation methods, the therapeutic loading and release and the various therapeutic applications.https://www.mdpi.com/1422-0067/23/15/8581nanotechnologynanofibersdrug loadingbiomedicinetherapeutic applications |
| spellingShingle | Ivana Jarak Inês Silva Cátia Domingues Ana Isabel Santos Francisco Veiga Ana Figueiras Nanofiber Carriers of Therapeutic Load: Current Trends International Journal of Molecular Sciences nanotechnology nanofibers drug loading biomedicine therapeutic applications |
| title | Nanofiber Carriers of Therapeutic Load: Current Trends |
| title_full | Nanofiber Carriers of Therapeutic Load: Current Trends |
| title_fullStr | Nanofiber Carriers of Therapeutic Load: Current Trends |
| title_full_unstemmed | Nanofiber Carriers of Therapeutic Load: Current Trends |
| title_short | Nanofiber Carriers of Therapeutic Load: Current Trends |
| title_sort | nanofiber carriers of therapeutic load current trends |
| topic | nanotechnology nanofibers drug loading biomedicine therapeutic applications |
| url | https://www.mdpi.com/1422-0067/23/15/8581 |
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