Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility Pattern
Introduction: Diabetes mellitus has adverse effect on genitourinary system and patients suffering from diabetes mellitus are more prone to have urinary tract infection with risk of potentially harmful extension of infection to kidneys. Aim: The study was carried out to find the prevalence of ur...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Pvt. Ltd.
2012-06-01
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| Series: | National Journal of Laboratory Medicine |
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| Online Access: | http://www.njlm.net/articles/PDF/1942/7-4332.pdf |
| _version_ | 1811284292131618816 |
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| author | Vishal Sharma Vishal Gupta Mridula Mittal |
| author_facet | Vishal Sharma Vishal Gupta Mridula Mittal |
| author_sort | Vishal Sharma |
| collection | DOAJ |
| description | Introduction: Diabetes mellitus has adverse effect on
genitourinary system and patients suffering from diabetes
mellitus are more prone to have urinary tract infection with
risk of potentially harmful extension of infection to kidneys.
Aim: The study was carried out to find the prevalence
of uropathogens in diabetic patients and to study their
antibiotic susceptibility pattern.
Material and methods: Urine samples were collected from
270 diabetic patients (inpatients and outpatients) of our
hospital. The specimens were processed and examined for
the various uropathogens using the standard microbiological
procedures. Antibiotic susceptibility testing was performed
for various antibiotics by Kirby Bauer disc diffusion method
and the results were interpreted as per CLSI guidelines. The
data was tabulated and analyzed.
Results: Uropathogens were isolated in 118 patients with
females out numbering males (1.8:1). Escherichia coli was
the most frequent isolate (41.5%), followed by Klebsiella
species (14.4%), Proteus species (10.1%), Enterococci
(8.4%), Pseudomonas aeruginosa (6.7%), Staphylococcus
species (10.1%) and Candida albicans (8.4%). The isolates
showed moderate to high level of resistance to various
antibiotics tested.
Conclusions: Continuous surveillance of antibiotic
susceptibility patterns of uropathogens in diabetic patient
should be done to ensure rational use of antibiotics for
empirical and definitive treatment of urinary tract infections
in this vulnerable group. |
| first_indexed | 2024-04-13T02:26:26Z |
| format | Article |
| id | doaj.art-43d132a096fe487b84b03425d847f03c |
| institution | Directory Open Access Journal |
| issn | 2277-8551 2455-6882 |
| language | English |
| last_indexed | 2024-04-13T02:26:26Z |
| publishDate | 2012-06-01 |
| publisher | JCDR Research and Publications Pvt. Ltd. |
| record_format | Article |
| series | National Journal of Laboratory Medicine |
| spelling | doaj.art-43d132a096fe487b84b03425d847f03c2022-12-22T03:06:45ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822012-06-0111262810.7860/NJLM/2012/4332:1942Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility PatternVishal Sharma0Vishal Gupta1Mridula Mittal2Corresponding AuthorAssistant Professor, Department of Community Medicine, Chintpurni Medical College and Hospital, Pathankot, Punjab, India.Assistant Professor, Department of Physiology, Chintpurni Medical College and Hospital, Pathankot, Punjab, IndiaIntroduction: Diabetes mellitus has adverse effect on genitourinary system and patients suffering from diabetes mellitus are more prone to have urinary tract infection with risk of potentially harmful extension of infection to kidneys. Aim: The study was carried out to find the prevalence of uropathogens in diabetic patients and to study their antibiotic susceptibility pattern. Material and methods: Urine samples were collected from 270 diabetic patients (inpatients and outpatients) of our hospital. The specimens were processed and examined for the various uropathogens using the standard microbiological procedures. Antibiotic susceptibility testing was performed for various antibiotics by Kirby Bauer disc diffusion method and the results were interpreted as per CLSI guidelines. The data was tabulated and analyzed. Results: Uropathogens were isolated in 118 patients with females out numbering males (1.8:1). Escherichia coli was the most frequent isolate (41.5%), followed by Klebsiella species (14.4%), Proteus species (10.1%), Enterococci (8.4%), Pseudomonas aeruginosa (6.7%), Staphylococcus species (10.1%) and Candida albicans (8.4%). The isolates showed moderate to high level of resistance to various antibiotics tested. Conclusions: Continuous surveillance of antibiotic susceptibility patterns of uropathogens in diabetic patient should be done to ensure rational use of antibiotics for empirical and definitive treatment of urinary tract infections in this vulnerable group.http://www.njlm.net/articles/PDF/1942/7-4332.pdfdiabetes mellitusgenitourinaryuropathogens |
| spellingShingle | Vishal Sharma Vishal Gupta Mridula Mittal Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility Pattern National Journal of Laboratory Medicine diabetes mellitus genitourinary uropathogens |
| title | Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility Pattern |
| title_full | Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility Pattern |
| title_fullStr | Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility Pattern |
| title_full_unstemmed | Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility Pattern |
| title_short | Prevalence Of Uropathogens In Diabetic Patients And Their Antimicrobial Susceptibility Pattern |
| title_sort | prevalence of uropathogens in diabetic patients and their antimicrobial susceptibility pattern |
| topic | diabetes mellitus genitourinary uropathogens |
| url | http://www.njlm.net/articles/PDF/1942/7-4332.pdf |
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