Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis
Objective The aim of this meta-analysis was to examine the association of ApoE polymorphism with the risk of developing PE. Methods A comprehensive search was carried out through PubMed, Scopus, and Embase. The ORs with corresponding 95% CIs were extracted. Fixed model was used for meta-analysis and...
| Hlavní autoři: | , , , , |
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| Médium: | Článek |
| Jazyk: | English |
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Taylor & Francis Group
2020-04-01
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| Edice: | Hypertension in Pregnancy |
| Témata: | |
| On-line přístup: | http://dx.doi.org/10.1080/10641955.2020.1753068 |
| _version_ | 1827814492643262464 |
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| author | Morteza Abyadeh Fatemeh Heydarinejad Maliheh Khakpash Yaser Asefi Sakineh Shab-Bidar |
| author_facet | Morteza Abyadeh Fatemeh Heydarinejad Maliheh Khakpash Yaser Asefi Sakineh Shab-Bidar |
| author_sort | Morteza Abyadeh |
| collection | DOAJ |
| description | Objective The aim of this meta-analysis was to examine the association of ApoE polymorphism with the risk of developing PE. Methods A comprehensive search was carried out through PubMed, Scopus, and Embase. The ORs with corresponding 95% CIs were extracted. Fixed model was used for meta-analysis and in case of existing heterogeneity a random-effects model was applied. Results Association of ApoE polymorphism with the risk of developing PE was not statistically significant (OR = 0.86, 95% CI: 0.67–1.11; OR = 0.92, 95%CI: 0.73–1.15, respectively for ε2 and ε4). Conclusion ApoE polymorphism might not be associated with the risk of PE. |
| first_indexed | 2024-03-11T23:46:55Z |
| format | Article |
| id | doaj.art-43d30b47288b4ee78d9a33e8d9bddb51 |
| institution | Directory Open Access Journal |
| issn | 1064-1955 1525-6065 |
| language | English |
| last_indexed | 2024-03-11T23:46:55Z |
| publishDate | 2020-04-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Hypertension in Pregnancy |
| spelling | doaj.art-43d30b47288b4ee78d9a33e8d9bddb512023-09-19T09:24:43ZengTaylor & Francis GroupHypertension in Pregnancy1064-19551525-60652020-04-0139219620210.1080/10641955.2020.17530681753068Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysisMorteza Abyadeh0Fatemeh Heydarinejad1Maliheh Khakpash2Yaser Asefi3Sakineh Shab-Bidar4Royan Institute for Stem Cell Biology and Technology, ACECRShahroud University of Medical SciencesShahroud University of Medical SciencesIslamic Azad UniversityTehran University of Medical Sciences (TUMS)Objective The aim of this meta-analysis was to examine the association of ApoE polymorphism with the risk of developing PE. Methods A comprehensive search was carried out through PubMed, Scopus, and Embase. The ORs with corresponding 95% CIs were extracted. Fixed model was used for meta-analysis and in case of existing heterogeneity a random-effects model was applied. Results Association of ApoE polymorphism with the risk of developing PE was not statistically significant (OR = 0.86, 95% CI: 0.67–1.11; OR = 0.92, 95%CI: 0.73–1.15, respectively for ε2 and ε4). Conclusion ApoE polymorphism might not be associated with the risk of PE.http://dx.doi.org/10.1080/10641955.2020.1753068apolipoprotein epolymorphismpreeclampsiameta-analysis |
| spellingShingle | Morteza Abyadeh Fatemeh Heydarinejad Maliheh Khakpash Yaser Asefi Sakineh Shab-Bidar Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis Hypertension in Pregnancy apolipoprotein e polymorphism preeclampsia meta-analysis |
| title | Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis |
| title_full | Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis |
| title_fullStr | Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis |
| title_full_unstemmed | Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis |
| title_short | Association of Apolipoprotein E gene polymorphism with Preeclampsia: a meta-analysis |
| title_sort | association of apolipoprotein e gene polymorphism with preeclampsia a meta analysis |
| topic | apolipoprotein e polymorphism preeclampsia meta-analysis |
| url | http://dx.doi.org/10.1080/10641955.2020.1753068 |
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