Icterus Neonatorum in Near-Term and Term Infants : An overview
Neonatal jaundice is the yellowish discoloration of the skin and/or sclerae of newborn infants caused by tissue deposition of bilirubin. Physiological jaundice is mild, unconjugated (indirect-reacting) bilirubinaemia, and affects nearly all newborns. Physiological jaundice levels typically peak at...
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| Format: | Article |
| Language: | English |
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Sultan Qaboos University
2012-05-01
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| Series: | Sultan Qaboos University Medical Journal |
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| Online Access: | https://journals.squ.edu.om/index.php/squmj/article/view/1668 |
| _version_ | 1818758262674161664 |
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| author | Rehan Ali Shakeel Ahmed Maqbool Qadir Khalil Ahmad |
| author_facet | Rehan Ali Shakeel Ahmed Maqbool Qadir Khalil Ahmad |
| author_sort | Rehan Ali |
| collection | DOAJ |
| description | Neonatal jaundice is the yellowish discoloration of the skin and/or sclerae of newborn infants caused by tissue deposition of bilirubin. Physiological jaundice is mild, unconjugated (indirect-reacting) bilirubinaemia, and affects nearly all newborns. Physiological jaundice levels typically peak at 5 to 6 mg/dL (86 to 103 µmol/L) at 72 to 96 hours of age, and do not exceed 17 to 18 mg/dL (291–308 µmol/L). Levels may not peak until seven days of age in Asian infants, or in infants born at 35 to 37 weeks’ gestation. Higher levels of unconjugated hyperbilirubinaemia are considered pathological and occur in a variety of conditions. The clinical features and management of unconjugated hyperbilirubinaemia in healthy near-term and term infants, as well as bilirubin toxicity and the prevention of kernicterus, are reviewed here. The pathogenesis and aetiology of this disorder are discussed separately. |
| first_indexed | 2024-12-18T06:24:02Z |
| format | Article |
| id | doaj.art-43d56f424e3a4244aaafb40bb4611894 |
| institution | Directory Open Access Journal |
| issn | 2075-051X 2075-0528 |
| language | English |
| last_indexed | 2024-12-18T06:24:02Z |
| publishDate | 2012-05-01 |
| publisher | Sultan Qaboos University |
| record_format | Article |
| series | Sultan Qaboos University Medical Journal |
| spelling | doaj.art-43d56f424e3a4244aaafb40bb46118942022-12-21T21:18:06ZengSultan Qaboos UniversitySultan Qaboos University Medical Journal2075-051X2075-05282012-05-011221531601593Icterus Neonatorum in Near-Term and Term Infants : An overviewRehan Ali0Shakeel Ahmed1Maqbool Qadir2Khalil Ahmad3Department of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, PakistanDepartment of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, PakistanDepartment of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, PakistanDepartment of Paediatrics and Child Health, Aga Khan University Hospital, Karachi, PakistanNeonatal jaundice is the yellowish discoloration of the skin and/or sclerae of newborn infants caused by tissue deposition of bilirubin. Physiological jaundice is mild, unconjugated (indirect-reacting) bilirubinaemia, and affects nearly all newborns. Physiological jaundice levels typically peak at 5 to 6 mg/dL (86 to 103 µmol/L) at 72 to 96 hours of age, and do not exceed 17 to 18 mg/dL (291–308 µmol/L). Levels may not peak until seven days of age in Asian infants, or in infants born at 35 to 37 weeks’ gestation. Higher levels of unconjugated hyperbilirubinaemia are considered pathological and occur in a variety of conditions. The clinical features and management of unconjugated hyperbilirubinaemia in healthy near-term and term infants, as well as bilirubin toxicity and the prevention of kernicterus, are reviewed here. The pathogenesis and aetiology of this disorder are discussed separately.https://journals.squ.edu.om/index.php/squmj/article/view/1668newbornicterushyperbilirubinaemiajaundice. |
| spellingShingle | Rehan Ali Shakeel Ahmed Maqbool Qadir Khalil Ahmad Icterus Neonatorum in Near-Term and Term Infants : An overview Sultan Qaboos University Medical Journal newborn icterus hyperbilirubinaemia jaundice. |
| title | Icterus Neonatorum in Near-Term and Term Infants : An overview |
| title_full | Icterus Neonatorum in Near-Term and Term Infants : An overview |
| title_fullStr | Icterus Neonatorum in Near-Term and Term Infants : An overview |
| title_full_unstemmed | Icterus Neonatorum in Near-Term and Term Infants : An overview |
| title_short | Icterus Neonatorum in Near-Term and Term Infants : An overview |
| title_sort | icterus neonatorum in near term and term infants an overview |
| topic | newborn icterus hyperbilirubinaemia jaundice. |
| url | https://journals.squ.edu.om/index.php/squmj/article/view/1668 |
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