Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions
Background: Preoperative marking of impalpable breast lesions is crucial for limiting false negative results and reducing the size of the resected breast tissue, thus improving cosmesis. The aim of this study was to evaluate wire localization versus intralesional methylene blue marking for surgical...
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| Format: | Article |
| Language: | English |
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Shiraz University of Medical Sciences
2023-10-01
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| Series: | Middle East Journal of Cancer |
| Subjects: | |
| Online Access: | https://mejc.sums.ac.ir/article_49273_653b32fd623c308c9bde17df67039121.pdf |
| _version_ | 1797663398936182784 |
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| author | Rabie Ramadan Tarek El-Fayoumy Rafik Ibrahim Hany Saifeldin Haytham Fayed |
| author_facet | Rabie Ramadan Tarek El-Fayoumy Rafik Ibrahim Hany Saifeldin Haytham Fayed |
| author_sort | Rabie Ramadan |
| collection | DOAJ |
| description | Background: Preoperative marking of impalpable breast lesions is crucial for limiting false negative results and reducing the size of the resected breast tissue, thus improving cosmesis. The aim of this study was to evaluate wire localization versus intralesional methylene blue marking for surgical excision of impalpable breast lesions regarding the success of localization, cost, and limitations of both techniques.Method: This prospective cohort study included 50 patients with impalpable breast lesions or an area of suspicious microcalcification who were scheduled for surgical excision in the period between June 2020 and December 2021. Patients were randomly allocated into two groups: group I included 25 patients for surgical excision after preoperative ultrasound-guided methylene blue marking. Group II included 25 patients scheduled for surgical excision after preoperative guide wire localization under radiological guidance.Results: Localization by methylene blue injection has been associated with significantly shorter time of operation with mean duration (P = 0.018) and much reduced cost in comparison with guide wire (P < 0.001). Postoperative pain, reactions, ecchymosis, accuracy of localization, margin status, and patient satisfaction did not vary significantly between both groups.Conclusion: Localization by methylene blue injection is not only equally successful to guide wire in locating and identifying impalpable breast lesions for surgical excision, but also is significantly less costly and associated with a shorter duration of operation. |
| first_indexed | 2024-03-11T19:13:59Z |
| format | Article |
| id | doaj.art-43d8dd4b90fb4b879e505ca5cefbb2be |
| institution | Directory Open Access Journal |
| issn | 2008-6709 2008-6687 |
| language | English |
| last_indexed | 2024-03-11T19:13:59Z |
| publishDate | 2023-10-01 |
| publisher | Shiraz University of Medical Sciences |
| record_format | Article |
| series | Middle East Journal of Cancer |
| spelling | doaj.art-43d8dd4b90fb4b879e505ca5cefbb2be2023-10-09T09:02:56ZengShiraz University of Medical SciencesMiddle East Journal of Cancer2008-67092008-66872023-10-0114455956910.30476/mejc.2023.95919.179649273Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast LesionsRabie Ramadan0Tarek El-Fayoumy1Rafik Ibrahim2Hany Saifeldin3Haytham Fayed4Department of Surgery, Medical Research Institute, Alexandria University, Alexandria, EgyptDepartment of Surgery, Faculty of Medicine, Alexandria University, Alexandria, EgyptDepartment of Radiology, Faculty of Medicine, Alexandria University, Alexandria, EgyptDepartment of Surgery, Medical Research Institute, Alexandria University, Alexandria, EgyptDepartment of Surgery, Faculty of Medicine, Alexandria University, Alexandria, EgyptBackground: Preoperative marking of impalpable breast lesions is crucial for limiting false negative results and reducing the size of the resected breast tissue, thus improving cosmesis. The aim of this study was to evaluate wire localization versus intralesional methylene blue marking for surgical excision of impalpable breast lesions regarding the success of localization, cost, and limitations of both techniques.Method: This prospective cohort study included 50 patients with impalpable breast lesions or an area of suspicious microcalcification who were scheduled for surgical excision in the period between June 2020 and December 2021. Patients were randomly allocated into two groups: group I included 25 patients for surgical excision after preoperative ultrasound-guided methylene blue marking. Group II included 25 patients scheduled for surgical excision after preoperative guide wire localization under radiological guidance.Results: Localization by methylene blue injection has been associated with significantly shorter time of operation with mean duration (P = 0.018) and much reduced cost in comparison with guide wire (P < 0.001). Postoperative pain, reactions, ecchymosis, accuracy of localization, margin status, and patient satisfaction did not vary significantly between both groups.Conclusion: Localization by methylene blue injection is not only equally successful to guide wire in locating and identifying impalpable breast lesions for surgical excision, but also is significantly less costly and associated with a shorter duration of operation.https://mejc.sums.ac.ir/article_49273_653b32fd623c308c9bde17df67039121.pdfbreast neoplasmsmethylene blueguide wiresurgical margin |
| spellingShingle | Rabie Ramadan Tarek El-Fayoumy Rafik Ibrahim Hany Saifeldin Haytham Fayed Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions Middle East Journal of Cancer breast neoplasms methylene blue guide wire surgical margin |
| title | Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions |
| title_full | Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions |
| title_fullStr | Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions |
| title_full_unstemmed | Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions |
| title_short | Wire Localization versus Intralesional Methylene Blue Marking for Surgical Excision of Impalpable Breast Lesions |
| title_sort | wire localization versus intralesional methylene blue marking for surgical excision of impalpable breast lesions |
| topic | breast neoplasms methylene blue guide wire surgical margin |
| url | https://mejc.sums.ac.ir/article_49273_653b32fd623c308c9bde17df67039121.pdf |
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