Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan.
<h4>Background</h4>The reduction in severe and moderate acute malnutrition (SAM and MAM) rates in Pakistan has been sub-optimal compared to other low-and middle-income countries (LMICs). Specially-formulated products have been designed globally to manage SAM and MAM, such as ready-to-use...
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| Format: | Article |
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Public Library of Science (PLoS)
2023-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287962&type=printable |
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| author | Azza Sarfraz Sheraz Ahmed Sajid Muhammad Najeeb Rehman Sanam Iram Soomro Khaliq Qureshi Sadaf Jakhro Fayaz Umrani Adam Greene Sana Syed Sean R Moore Syed Asad Ali |
| author_facet | Azza Sarfraz Sheraz Ahmed Sajid Muhammad Najeeb Rehman Sanam Iram Soomro Khaliq Qureshi Sadaf Jakhro Fayaz Umrani Adam Greene Sana Syed Sean R Moore Syed Asad Ali |
| author_sort | Azza Sarfraz |
| collection | DOAJ |
| description | <h4>Background</h4>The reduction in severe and moderate acute malnutrition (SAM and MAM) rates in Pakistan has been sub-optimal compared to other low-and middle-income countries (LMICs). Specially-formulated products have been designed globally to manage SAM and MAM, such as ready-to-use therapeutic food (RUTF) and ready-to-use supplementary food (RUSF), with variable efficacies. RUTF is primarily produced and patented in industrialized countries, raising supply challenges in resource-constrained regions with a high burden of acute malnutrition. RUSF minimizes costs by using locally-available ingredients while providing similar nutritional value. In this study, we compared the efficacy, side effects, and compliance of two months of supplementation with either RUTF or RUSF.<h4>Methods</h4>Children aged nine months in the rural district of Matiari, Pakistan, with a weight-for-height z-score (WHZ) <-2 received either RUTF (500 kcal sachet) for two months in 2015 or RUSF (520 kcal sachet) for two months in 2018.<h4>Results</h4>The RUSF group had a higher height gain and mid-upper arm circumferences (MUAC) score. Higher compliance was noted with lower side effects in the RUSF group. A higher compliance rate did correlate with the growth parameters in respective groups.<h4>Conclusion</h4>Our study found that both RUTF and RUSF partially improve the anthropometric status of acutely malnourished children, with neither being superior to the other. |
| first_indexed | 2024-03-11T16:51:14Z |
| format | Article |
| id | doaj.art-43da325be0ec4e309c11776809c585ad |
| institution | Directory Open Access Journal |
| issn | 1932-6203 |
| language | English |
| last_indexed | 2024-03-11T16:51:14Z |
| publishDate | 2023-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj.art-43da325be0ec4e309c11776809c585ad2023-10-21T05:31:53ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01187e028796210.1371/journal.pone.0287962Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan.Azza SarfrazSheraz AhmedSajid MuhammadNajeeb RehmanSanam Iram SoomroKhaliq QureshiSadaf JakhroFayaz UmraniAdam GreeneSana SyedSean R MooreSyed Asad Ali<h4>Background</h4>The reduction in severe and moderate acute malnutrition (SAM and MAM) rates in Pakistan has been sub-optimal compared to other low-and middle-income countries (LMICs). Specially-formulated products have been designed globally to manage SAM and MAM, such as ready-to-use therapeutic food (RUTF) and ready-to-use supplementary food (RUSF), with variable efficacies. RUTF is primarily produced and patented in industrialized countries, raising supply challenges in resource-constrained regions with a high burden of acute malnutrition. RUSF minimizes costs by using locally-available ingredients while providing similar nutritional value. In this study, we compared the efficacy, side effects, and compliance of two months of supplementation with either RUTF or RUSF.<h4>Methods</h4>Children aged nine months in the rural district of Matiari, Pakistan, with a weight-for-height z-score (WHZ) <-2 received either RUTF (500 kcal sachet) for two months in 2015 or RUSF (520 kcal sachet) for two months in 2018.<h4>Results</h4>The RUSF group had a higher height gain and mid-upper arm circumferences (MUAC) score. Higher compliance was noted with lower side effects in the RUSF group. A higher compliance rate did correlate with the growth parameters in respective groups.<h4>Conclusion</h4>Our study found that both RUTF and RUSF partially improve the anthropometric status of acutely malnourished children, with neither being superior to the other.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287962&type=printable |
| spellingShingle | Azza Sarfraz Sheraz Ahmed Sajid Muhammad Najeeb Rehman Sanam Iram Soomro Khaliq Qureshi Sadaf Jakhro Fayaz Umrani Adam Greene Sana Syed Sean R Moore Syed Asad Ali Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan. PLoS ONE |
| title | Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan. |
| title_full | Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan. |
| title_fullStr | Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan. |
| title_full_unstemmed | Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan. |
| title_short | Standard RUTF vs. locally-made RUSF for acutely malnourished children: A quasi-experimental comparison of the impact on growth and compliance in a rural community of Pakistan. |
| title_sort | standard rutf vs locally made rusf for acutely malnourished children a quasi experimental comparison of the impact on growth and compliance in a rural community of pakistan |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0287962&type=printable |
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