Blocking Metabotropic Glutamate Receptor Subtype 7 via the Venus Flytrap Domain Promotes a Chronic Stress-Resilient Phenotype in Mice

Blocking Metabotropic Glutamate Receptor Subtype 7 via the Venus Flytrap Domain Promotes a Chronic Stress-Resilient Phenotype in Mice

Chronic psychosocial stress participates prominently in the etiology of various psychiatric conditions and comorbid somatic pathologies; however, suitable pharmacotherapy of these disorders is still of high medical need. During the last few decades, research on mGlu receptors advanced remarkably and...

书目详细资料
Main Authors:	Karolyne A. R. Estrela, Lisa Senninger, Josephine Arndt, Melanie Kabas, Ferdinand Schmid, Larissa Dillmann, Sophia Auer, Thomas Stepfer, Peter J. Flor, Nicole Uschold-Schmidt
格式:	文件
语言:	English
出版:	MDPI AG 2022-06-01
丛编:	Cells
主题:	mGlu7 XAP044 chronic psychosocial stress chronic subordinate colony housing
在线阅读:	https://www.mdpi.com/2073-4409/11/11/1817

相似书籍

Inhibition of the Interaction Between Group I Metabotropic Glutamate Receptors and PDZ-Domain Proteins Prevents Hippocampal Long-Term Depression, but Not Long-Term Potentiation
由: Sergey Neyman, et al.
出版: (2019-04-01)

Targeting metabotropic glutamate receptors for novel treatments of schizophrenia
由: James Maksymetz, et al.
出版: (2017-04-01)

Phosphorylation and regulation of group II metabotropic glutamate receptors (mGlu2/3) in neurons
由: Li-Min Mao, et al.
出版: (2022-11-01)

Glutamate Metabotropic Receptor Type 3 (mGlu3) Localization in the Rat Prelimbic Medial Prefrontal Cortex
由: Elizabeth Woo, et al.
出版: (2022-04-01)

Group II metabotropic glutamate receptors as targets for novel antipsychotic drugs
由: Carolina eMuguruza, et al.
出版: (2016-05-01)

Dissociation of impulsive traits by subthalamic metabotropic glutamate receptor 4
由: Lukasz Piszczek, et al.
出版: (2022-01-01)

Metabotropic Glutamate Receptor Subtype 5 in Alcohol-Induced Negative Affect
由: Chelsea R. Kasten, et al.
出版: (2019-07-01)

Potential of Glutamate-Based Drug Discovery for Next Generation Antidepressants
由: Shigeyuki Chaki, et al.
出版: (2015-09-01)

Shedding of Microvesicles from Microglia Contributes to the Effects Induced by Metabotropic Glutamate Receptor 5 Activation on Neuronal Death
由: Martina Beneventano, et al.
出版: (2017-11-01)

Epigenetic Alterations in Prenatal Stress Mice as an Endophenotype Model for Schizophrenia: Role of Metabotropic Glutamate 2/3 Receptors
由: Francesco Matrisciano, et al.
出版: (2018-11-01)

Developmentally Regulated Modulation of Lumbar Motoneurons by Metabotropic Glutamate Receptors: A Cellular and Behavioral Analysis in Newborn Mice
由: Camille Quilgars, et al.
出版: (2021-12-01)

Could MDMA Promote Stemness Characteristics in Mouse Embryonic Stem Cells via mGlu5 Metabotropic Glutamate Receptors?
由: Rokhsareh Meamar, et al.
出版: (2012-01-01)

Computational Drug Design Applied to the Study of Metabotropic Glutamate Receptors
由: Claudia Llinas del Torrent, et al.
出版: (2019-03-01)

Interplay between metabotropic glutamate type 4 and adenosine type 1 receptors modulate synaptic transmission in the cerebellar cortex
由: Simon Bossi, et al.
出版: (2024-08-01)

Design, Synthesis and Characterization of a New Series of Fluorescent Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulators
由: Víctor Fernández-Dueñas, et al.
出版: (2020-03-01)

Microbiome Profiling Reveals Gut Dysbiosis in the Metabotropic Glutamate Receptor 5 Knockout Mouse Model of Schizophrenia
由: Carolina Gubert, et al.
出版: (2020-10-01)

Effect of the Metabotropic Glutamate Receptor Type 5 Negative Allosteric Modulator Dipraglurant on Motor and Non-Motor Symptoms of Parkinson’s Disease
由: Mark P. Epping-Jordan, et al.
出版: (2023-03-01)

Genetic deletion of mGlu2 metabotropic glutamate receptors improves the short-term outcome of cerebral transient focal ischemia
由: Federica Mastroiacovo, et al.
出版: (2017-08-01)

N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors
由: Bernabucci Matteo, et al.
出版: (2012-10-01)

Preclinical disposition of MGS0274 besylate, a prodrug of a potent group II metabotropic glutamate receptor agonist MGS0008 for the treatment of schizophrenia
由: Kohnosuke Kinoshita, et al.
出版: (2019-10-01)

Distinct Time-Course of Alterations of Groups I and II Metabotropic Glutamate Receptor and GABAergic Receptor Expression Along the Dorsoventral Hippocampal Axis in an Animal Model of Psychosis
由: Valentyna Dubovyk, et al.
出版: (2019-05-01)

Antipsychotic profiles of TASP0443294, a novel and orally active positive allosteric modulator of metabotropic glutamate 2 receptor
由: Hirohiko Hikichi, et al.
出版: (2015-03-01)

Investigation of the Roles of the Adenosine A(2A) and Metabotropic Glutamate Receptor Type 5 (mGlu5) Receptors in Prepulse Inhibition and CREB Signaling in a Heritable Rodent Model of Psychosis
由: Anthony M. Cuozzo, et al.
出版: (2025-01-01)

The Metabotropic Glutamate 5 Receptor in Sleep and Wakefulness: Focus on the Cortico-Thalamo-Cortical Oscillations
由: Richard Teke Ngomba, et al.
出版: (2023-06-01)

The Impact of LY487379 or CDPPB on eNOS Expression in the Mouse Brain and the Effect of Joint Administration of Compounds with NO<sup>•</sup> Releasers on MK-801- or Scopolamine-Driven Cognitive Dysfunction in Mice
由: Agata Płoska, et al.
出版: (2024-01-01)

Effects of the Positive Allosteric Modulator of Metabotropic Glutamate Receptor 5, VU-29, on Maintenance Association between Environmental Cues and Rewarding Properties of Ethanol in Rats
由: Marta Marszalek-Grabska, et al.
出版: (2020-05-01)

Fragile X mental retardation protein (FMRP) and metabotropic glutamate receptor subtype 5 (mGlu5) control stress granule formation in astrocytes
由: B. Di Marco, et al.
出版: (2021-07-01)

Emerging Trends in Pain Modulation by Metabotropic Glutamate Receptors
由: Vanessa Pereira, et al.
出版: (2019-01-01)

Loss-of-Function Models of the Metabotropic Glutamate Receptor Genes Grm8a and Grm8b Display Distinct Behavioral Phenotypes in Zebrafish Larvae (Danio rerio)
由: Teresa M. Lüffe, et al.
出版: (2022-06-01)

Role of the G Protein-Coupled Receptor, mGlu1, in Melanoma Development
由: Janet Wangari-Talbot, et al.
出版: (2010-08-01)

Dạy và học định nghĩa chính xác về giới hạn của hàm số thông qua quá trình mô hình hóa toán học
由: Lê Thái Bảo Thiên Trung, et al.
出版: (2017-08-01)

Activation of Metabotropic Glutamate Receptor (mGlu<sub>2</sub>) and Muscarinic Receptors (M<sub>1</sub>, M<sub>4</sub>, and M<sub>5</sub>), Alone or in Combination, and Its Impact on the Acquisition and Retention of Learning in the Morris Water Maze, NMDA Expression and cGMP Synthesis
由: Joanna M. Wierońska, et al.
出版: (2023-06-01)

Nematodes of Backyard Deciduous Fruit Trees in Florida
由: Jimmy R. Rich, et al.
出版: (2007-03-01)

Can We Talk? Improving Couples' Communication
由: Eboni J. Baugh, et al.
出版: (2010-04-01)

Nematodes of Backyard Deciduous Fruit Trees in Florida
由: Jimmy R. Rich, et al.
出版: (2007-03-01)

Can We Talk? Improving Couples' Communication
由: Eboni J. Baugh, et al.
出版: (2010-04-01)

Can We Talk? Improving Couples' Communication
由: Eboni J. Baugh, et al.
出版: (2010-04-01)

Nematodes of Backyard Deciduous Fruit Trees in Florida
由: Jimmy R. Rich, et al.
出版: (2007-03-01)

Genetic inactivation of mGlu5 receptor improves motor coordination in the Grm1crv4 mouse model of SCAR13 ataxia
由: Simone Bossi, et al.
出版: (2018-01-01)

Phương pháp hàm đặc trưng cho một số định lí giới hạn trong xác suất
由: Lê Trường Giang, et al.
出版: (2017-11-01)