Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques
ABSTRACT Objective To evaluate the predictive capacity for pregnancy of the progesterone level on the day of administering human chorionic gonadotropin, in women submitted to assisted reproductive techniques. Methods An observational study with 914 women submitted to assisted reproductive techni...
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Instituto Israelita de Ensino e Pesquisa Albert Einstein
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000300273&lng=en&tlng=en |
| _version_ | 1818312017169088512 |
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| author | Renato de Oliveira Fernanda Godoy Cabral Waldemar de Almeida Pereira Carvalho Emerson Barchi Cordts Bianca Bianco Caio Parente Barbosa |
| author_facet | Renato de Oliveira Fernanda Godoy Cabral Waldemar de Almeida Pereira Carvalho Emerson Barchi Cordts Bianca Bianco Caio Parente Barbosa |
| author_sort | Renato de Oliveira |
| collection | DOAJ |
| description | ABSTRACT Objective To evaluate the predictive capacity for pregnancy of the progesterone level on the day of administering human chorionic gonadotropin, in women submitted to assisted reproductive techniques. Methods An observational study with 914 women submitted to assisted reproductive techniques from August 2014 to June 2016. Results Total pregnancy rate was 34.58%; in that, the pregnancy rate in women <35 years, between 35 and 38, and >38 years was, respectively, 42.3%, 38.7% and 16.1% (p<0.001). For embryo transfer in the same cycle, and progesterone of 1.3ng/dL, sensitivity was 4.78%, specificity, 84.18%, accuracy, 56.72%, positive likelihood ratio of 0.3019, and negative likelihood ratio of 1.1312, with receiver operating characteristic curve of 0.46 (95%CI: 0.42-0.49). Conclusion The progesterone level on the day of administering human chorionic gonadotropin of 1.3ng/dL differs from that empirically adopted at the study site (1.7ng/dL), and has a better predictive capacity for pregnancy in the patients studied. However, the low sensitivity of this examination raises questions about its real importance. |
| first_indexed | 2024-12-13T08:11:09Z |
| format | Article |
| id | doaj.art-43dc39da45d54fa88d9100b242362759 |
| institution | Directory Open Access Journal |
| issn | 2317-6385 |
| language | English |
| last_indexed | 2024-12-13T08:11:09Z |
| publisher | Instituto Israelita de Ensino e Pesquisa Albert Einstein |
| record_format | Article |
| series | Einstein (São Paulo) |
| spelling | doaj.art-43dc39da45d54fa88d9100b2423627592022-12-21T23:54:13ZengInstituto Israelita de Ensino e Pesquisa Albert EinsteinEinstein (São Paulo)2317-638515327327710.1590/s1679-45082017ao4091S1679-45082017000300273Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniquesRenato de OliveiraFernanda Godoy CabralWaldemar de Almeida Pereira CarvalhoEmerson Barchi CordtsBianca BiancoCaio Parente BarbosaABSTRACT Objective To evaluate the predictive capacity for pregnancy of the progesterone level on the day of administering human chorionic gonadotropin, in women submitted to assisted reproductive techniques. Methods An observational study with 914 women submitted to assisted reproductive techniques from August 2014 to June 2016. Results Total pregnancy rate was 34.58%; in that, the pregnancy rate in women <35 years, between 35 and 38, and >38 years was, respectively, 42.3%, 38.7% and 16.1% (p<0.001). For embryo transfer in the same cycle, and progesterone of 1.3ng/dL, sensitivity was 4.78%, specificity, 84.18%, accuracy, 56.72%, positive likelihood ratio of 0.3019, and negative likelihood ratio of 1.1312, with receiver operating characteristic curve of 0.46 (95%CI: 0.42-0.49). Conclusion The progesterone level on the day of administering human chorionic gonadotropin of 1.3ng/dL differs from that empirically adopted at the study site (1.7ng/dL), and has a better predictive capacity for pregnancy in the patients studied. However, the low sensitivity of this examination raises questions about its real importance.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000300273&lng=en&tlng=enGravidezGonadotropina coriônicaProgesteronaTécnicas de reprodução assistida |
| spellingShingle | Renato de Oliveira Fernanda Godoy Cabral Waldemar de Almeida Pereira Carvalho Emerson Barchi Cordts Bianca Bianco Caio Parente Barbosa Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques Einstein (São Paulo) Gravidez Gonadotropina coriônica Progesterona Técnicas de reprodução assistida |
| title | Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques |
| title_full | Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques |
| title_fullStr | Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques |
| title_full_unstemmed | Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques |
| title_short | Progesterone level on the day of hCG administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques |
| title_sort | progesterone level on the day of hcg administration in relation to the pregnancy rates of patients undergoing assisted reproduction techniques |
| topic | Gravidez Gonadotropina coriônica Progesterona Técnicas de reprodução assistida |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1679-45082017000300273&lng=en&tlng=en |
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