The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions
Cow's milk allergy is one of the most commonly reported childhood food allergies, with increasing incidence, persistence and severity in many countries across the world. The World Allergy Organization Special Committee on Food Allergy has identified cow's milk allergy as an area in need of...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-01-01
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| Series: | World Allergy Organization Journal |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1939455119303679 |
| _version_ | 1811263805069459456 |
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| author | Adam Fox J. Andrew Bird Alessandro Fiocchi Jan Knol Rosan Meyer Seppo Salminen Gong Sitang Hania Szajewska Nikolaos Papadopoulos |
| author_facet | Adam Fox J. Andrew Bird Alessandro Fiocchi Jan Knol Rosan Meyer Seppo Salminen Gong Sitang Hania Szajewska Nikolaos Papadopoulos |
| author_sort | Adam Fox |
| collection | DOAJ |
| description | Cow's milk allergy is one of the most commonly reported childhood food allergies, with increasing incidence, persistence and severity in many countries across the world. The World Allergy Organization Special Committee on Food Allergy has identified cow's milk allergy as an area in need of a rationale-based approach in order to make progress against what it considered an onerous problem, with worldwide public health impact. There is growing interest in the potential role of the gut microbiota in the early programming and development of immune responses and allergy. This discussion paper considers the rationale and available evidence for modulation of the gut microbiota and for the use of synbiotics in the management of infants at risk of, or living with cow's milk allergy and summarizes remaining research questions that need to be answered for the development of evidence-based recommendations. Keywords: Cow's milk allergy, Allergy, Microbiota, Bifidobacteria, Lactobacilli, Synbiotic, Probiotic, Prebiotic, IgE, World Allergy Organization, Anaphylaxis, Dysbiosis |
| first_indexed | 2024-04-12T19:51:50Z |
| format | Article |
| id | doaj.art-43dd2d0753ef4e498c43f8a2044d0f03 |
| institution | Directory Open Access Journal |
| issn | 1939-4551 |
| language | English |
| last_indexed | 2024-04-12T19:51:50Z |
| publishDate | 2019-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | World Allergy Organization Journal |
| spelling | doaj.art-43dd2d0753ef4e498c43f8a2044d0f032022-12-22T03:18:48ZengElsevierWorld Allergy Organization Journal1939-45512019-01-01125The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questionsAdam Fox0J. Andrew Bird1Alessandro Fiocchi2Jan Knol3Rosan Meyer4Seppo Salminen5Gong Sitang6Hania Szajewska7Nikolaos Papadopoulos8Dept of Paediatric Allergy, Guy’s & St Thomas’ Hospitals NHS Foundation Trust, Westminster Bridge, London SE1 7EH, United Kingdom; Corresponding author. Dept of Paediatric Allergy, Guy’s & St Thomas’ Hospitals NHS Foundation Trust, Westminster Bridge, London SE1 7EH, United Kingdom.University of Texas Southwestern Medical Center, Department of Pediatrics, Division of Allergy and Immunology, 5323 Harry Hines Blvd, Dallas, TX 75390-9063, USAAllergy Unit, Bambino Gesù Children's Hospital, IRCCS, Piazza Sant'Onofrio 4, 00165 Rome, ItalyWageningen University, Stippeneng 4, 6708 WE Wageningen, the NetherlandsImperial College, Dept Paediatrics, London, UKFunctional Foods Forum, Faculty of Medicine, Itäinen pitkäkatu 4A, 20014 Turku, FinlandGuangzhou Women and Children's Medical Center, Tianhe, Guangzhou, 510620, ChinaDepartment of Paediatrics, The Medical University of Warsaw, 02-091 Warsaw, Zwiriki i Wigury 63A, PolandProfessor of Allergy & Paediatric Allergy Division of Infection, Immunity & Respiratory Medicine, University of Manchester, 5th Floor (Research), Royal Manchester Childrens Hospital, Manchester M13 9WL, UKCow's milk allergy is one of the most commonly reported childhood food allergies, with increasing incidence, persistence and severity in many countries across the world. The World Allergy Organization Special Committee on Food Allergy has identified cow's milk allergy as an area in need of a rationale-based approach in order to make progress against what it considered an onerous problem, with worldwide public health impact. There is growing interest in the potential role of the gut microbiota in the early programming and development of immune responses and allergy. This discussion paper considers the rationale and available evidence for modulation of the gut microbiota and for the use of synbiotics in the management of infants at risk of, or living with cow's milk allergy and summarizes remaining research questions that need to be answered for the development of evidence-based recommendations. Keywords: Cow's milk allergy, Allergy, Microbiota, Bifidobacteria, Lactobacilli, Synbiotic, Probiotic, Prebiotic, IgE, World Allergy Organization, Anaphylaxis, Dysbiosishttp://www.sciencedirect.com/science/article/pii/S1939455119303679 |
| spellingShingle | Adam Fox J. Andrew Bird Alessandro Fiocchi Jan Knol Rosan Meyer Seppo Salminen Gong Sitang Hania Szajewska Nikolaos Papadopoulos The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions World Allergy Organization Journal |
| title | The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions |
| title_full | The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions |
| title_fullStr | The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions |
| title_full_unstemmed | The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions |
| title_short | The potential for pre-, pro- and synbiotics in the management of infants at risk of cow's milk allergy or with cow's milk allergy: An exploration of the rationale, available evidence and remaining questions |
| title_sort | potential for pre pro and synbiotics in the management of infants at risk of cow s milk allergy or with cow s milk allergy an exploration of the rationale available evidence and remaining questions |
| url | http://www.sciencedirect.com/science/article/pii/S1939455119303679 |
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