A pilot study on genetic variation in purine-rich elements in the nephrin gene promoter in type 2 diabetic patients

A pilot study on genetic variation in purine-rich elements in the nephrin gene promoter in type 2 diabetic patients

Diabetic nephropathy (DN) is one of the major complications of type 2 diabetes and is associated with coronary disease. Nephrin, a protein mainly expressed in glomeruli, is decreased in DN and other kidney diseases. Since insulin levels are misregulated in type 2 diabetes, a possible connection betw...

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Bibliographic Details
Main Authors: RODRIGO GONZÁLEZ, ARES TIRADO, MONSERRAT BALANDA, MIRIAM ALVO, INÉS BARQUÍN, PILAR DURRUTY, SERGIO LOBOS, DANIELA SEELENFREUND
Format: Article
Language:English
Published: BMC 2007-01-01
Series:Biological Research
Subjects:
GAGA box
gene promoter
nephrin
polymorphism
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602007000400010

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