Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study
Background and Aims: Different additives have been used to prolong brachial plexus block. We evaluated the effect of adding dexmedetomidine to ropivacaine for supraclavicular brachial plexus blockade. The primary endpoints were the onset and duration of sensory and motor block and duration of analge...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2014-01-01
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| Series: | Saudi Journal of Anaesthesia |
| Subjects: | |
| Online Access: | http://www.saudija.org/article.asp?issn=1658-354X;year=2014;volume=8;issue=5;spage=72;epage=77;aulast=Das |
| _version_ | 1819178581858713600 |
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| author | Anjan Das Saikat Majumdar Susanta Halder Surajit Chattopadhyay Saswati Pal Ratul Kundu Subrata Kumar Mandal Sandip Chattopadhyay |
| author_facet | Anjan Das Saikat Majumdar Susanta Halder Surajit Chattopadhyay Saswati Pal Ratul Kundu Subrata Kumar Mandal Sandip Chattopadhyay |
| author_sort | Anjan Das |
| collection | DOAJ |
| description | Background and Aims: Different additives have been used to prolong brachial plexus block. We evaluated the effect of adding dexmedetomidine to ropivacaine for supraclavicular brachial plexus blockade. The primary endpoints were the onset and duration of sensory and motor block and duration of analgesia. Materials and Methods: A total of 84 patients (20-50 years) posted for elective forearm and hand surgery under supraclavicular brachial plexus block were divided into two equal groups (Group R and RD) in a randomized, double-blind fashion. In group RD (n = 42) 30 ml 0.5% ropivacaine +1 ml (100 μg) of dexmedetomidine and group R (n = 42) 30 ml 0.5% ropivacaine +1 ml normal saline were administered in supraclavicular block. Sensory and motor block onset times and block durations, time to first analgesic use, total analgesic need, postoperative visual analog scale (VAS), hemodynamics and side-effects were recorded for each patient. Results: Though with similar demographic profile in both groups, sensory and motor block in group RD (P < 0.05) was earlier than group R. Sensory and motor block duration and time to first analgesic use were significantly longer and the total need for rescue analgesics was lower in group RD (P < 0.05) than group R. Post-operative VAS value at 12 h were significantly lower in group RD (P < 0.05). Intra-operative hemodynamics were significantly lower in group RD (P < 0.05) without any appreciable side-effects. Conclusion: It can be concluded that adding dexmedetomidine to supraclavicular brachial plexus block increases the sensory and motor block duration and time to first analgesic use, and decreases total analgesic use with no side-effects. |
| first_indexed | 2024-12-22T21:44:50Z |
| format | Article |
| id | doaj.art-43df8745bab847bbbb8a3e9176831736 |
| institution | Directory Open Access Journal |
| issn | 1658-354X |
| language | English |
| last_indexed | 2024-12-22T21:44:50Z |
| publishDate | 2014-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Anaesthesia |
| spelling | doaj.art-43df8745bab847bbbb8a3e91768317362022-12-21T18:11:31ZengWolters Kluwer Medknow PublicationsSaudi Journal of Anaesthesia1658-354X2014-01-0185727710.4103/1658-354X.144082Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled studyAnjan DasSaikat MajumdarSusanta HalderSurajit ChattopadhyaySaswati PalRatul KunduSubrata Kumar MandalSandip ChattopadhyayBackground and Aims: Different additives have been used to prolong brachial plexus block. We evaluated the effect of adding dexmedetomidine to ropivacaine for supraclavicular brachial plexus blockade. The primary endpoints were the onset and duration of sensory and motor block and duration of analgesia. Materials and Methods: A total of 84 patients (20-50 years) posted for elective forearm and hand surgery under supraclavicular brachial plexus block were divided into two equal groups (Group R and RD) in a randomized, double-blind fashion. In group RD (n = 42) 30 ml 0.5% ropivacaine +1 ml (100 μg) of dexmedetomidine and group R (n = 42) 30 ml 0.5% ropivacaine +1 ml normal saline were administered in supraclavicular block. Sensory and motor block onset times and block durations, time to first analgesic use, total analgesic need, postoperative visual analog scale (VAS), hemodynamics and side-effects were recorded for each patient. Results: Though with similar demographic profile in both groups, sensory and motor block in group RD (P < 0.05) was earlier than group R. Sensory and motor block duration and time to first analgesic use were significantly longer and the total need for rescue analgesics was lower in group RD (P < 0.05) than group R. Post-operative VAS value at 12 h were significantly lower in group RD (P < 0.05). Intra-operative hemodynamics were significantly lower in group RD (P < 0.05) without any appreciable side-effects. Conclusion: It can be concluded that adding dexmedetomidine to supraclavicular brachial plexus block increases the sensory and motor block duration and time to first analgesic use, and decreases total analgesic use with no side-effects.http://www.saudija.org/article.asp?issn=1658-354X;year=2014;volume=8;issue=5;spage=72;epage=77;aulast=DasDexmedetomidineropivacainesupraclavicular brachial plexus block |
| spellingShingle | Anjan Das Saikat Majumdar Susanta Halder Surajit Chattopadhyay Saswati Pal Ratul Kundu Subrata Kumar Mandal Sandip Chattopadhyay Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study Saudi Journal of Anaesthesia Dexmedetomidine ropivacaine supraclavicular brachial plexus block |
| title | Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study |
| title_full | Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study |
| title_fullStr | Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study |
| title_full_unstemmed | Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study |
| title_short | Effect of dexmedetomidine as adjuvant in ropivacaine-induced supraclavicular brachial plexus block: A prospective, double-blinded and randomized controlled study |
| title_sort | effect of dexmedetomidine as adjuvant in ropivacaine induced supraclavicular brachial plexus block a prospective double blinded and randomized controlled study |
| topic | Dexmedetomidine ropivacaine supraclavicular brachial plexus block |
| url | http://www.saudija.org/article.asp?issn=1658-354X;year=2014;volume=8;issue=5;spage=72;epage=77;aulast=Das |
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