3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione
3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis starting with <i>o</i>-nitrobenzoyl sarcosine, acetoacetanilide and ethylamine. The compound showed moderate antibacterial activity against <i>S. aureus</i&...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-01-01
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| Series: | Molbank |
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| Online Access: | https://www.mdpi.com/1422-8599/2023/1/M1556 |
| _version_ | 1797609989047582720 |
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| author | Plamen Angelov Paraskeva Terziyska Danail Georgiev |
| author_facet | Plamen Angelov Paraskeva Terziyska Danail Georgiev |
| author_sort | Plamen Angelov |
| collection | DOAJ |
| description | 3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis starting with <i>o</i>-nitrobenzoyl sarcosine, acetoacetanilide and ethylamine. The compound showed moderate antibacterial activity against <i>S. aureus</i> and <i>E. coli</i>. |
| first_indexed | 2024-03-11T06:08:11Z |
| format | Article |
| id | doaj.art-43e091fde3b345ff8732a13ba5ca5f96 |
| institution | Directory Open Access Journal |
| issn | 1422-8599 |
| language | English |
| last_indexed | 2024-03-11T06:08:11Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molbank |
| spelling | doaj.art-43e091fde3b345ff8732a13ba5ca5f962023-11-17T12:49:22ZengMDPI AGMolbank1422-85992023-01-0120231M155610.3390/M15563-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dionePlamen Angelov0Paraskeva Terziyska1Danail Georgiev2Department of Organic Chemistry, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, BulgariaDepartment of Organic Chemistry, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, BulgariaDepartment of Biochemistry and Microbiology, University of Plovdiv Paisii Hilendarski, 24 Tsar Asen Str., 4000 Plovdiv, Bulgaria3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione was obtained as an unexpected product in a three-step synthesis starting with <i>o</i>-nitrobenzoyl sarcosine, acetoacetanilide and ethylamine. The compound showed moderate antibacterial activity against <i>S. aureus</i> and <i>E. coli</i>.https://www.mdpi.com/1422-8599/2023/1/M1556tetramic acidenaminepyrrolidine-2,4-dioneantibacterial |
| spellingShingle | Plamen Angelov Paraskeva Terziyska Danail Georgiev 3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione Molbank tetramic acid enamine pyrrolidine-2,4-dione antibacterial |
| title | 3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione |
| title_full | 3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione |
| title_fullStr | 3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione |
| title_full_unstemmed | 3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione |
| title_short | 3-(1-Ethylamino-ethylidene)-1-methyl-pyrrolidine-2,4-dione |
| title_sort | 3 1 ethylamino ethylidene 1 methyl pyrrolidine 2 4 dione |
| topic | tetramic acid enamine pyrrolidine-2,4-dione antibacterial |
| url | https://www.mdpi.com/1422-8599/2023/1/M1556 |
| work_keys_str_mv | AT plamenangelov 31ethylaminoethylidene1methylpyrrolidine24dione AT paraskevaterziyska 31ethylaminoethylidene1methylpyrrolidine24dione AT danailgeorgiev 31ethylaminoethylidene1methylpyrrolidine24dione |