HIF1α-dependent hypoxia response in myeloid cells requires IRE1α

Abstract Cellular adaptation to low oxygen tension triggers primitive pathways that ensure proper cell function. Conditions of hypoxia and low glucose are characteristic of injured tissues and hence successive waves of inflammatory cells must be suited to function under low oxygen tension and metabo...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Gaëlle Mawambo, Malika Oubaha, Yusuke Ichiyama, Guillaume Blot, Sergio Crespo-Garcia, Agnieszka Dejda, François Binet, Roberto Diaz-Marin, Christina Sawchyn, Mikhail Sergeev, Rachel Juneau, Randal J. Kaufman, El Bachir Affar, Frédérick A. Mallette, Ariel M. Wilson, Przemyslaw Sapieha
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: BMC 2023-06-01
Σειρά:Journal of Neuroinflammation
Θέματα:
Διαθέσιμο Online:https://doi.org/10.1186/s12974-023-02793-y