Design and Evaluation of Pegylated Large 3D Pore Ferrisilicate as a Potential Insulin Protein Therapy to Treat Diabetic Mellitus

Design and Evaluation of Pegylated Large 3D Pore Ferrisilicate as a Potential Insulin Protein Therapy to Treat Diabetic Mellitus

An iron-based SBA-16 mesoporous silica (ferrisilicate) with a large surface area and three-dimensional (3D) pores is explored as a potential insulin delivery vehicle with improved encapsulation and loading efficiency. Fe was incorporated into a framework of ferrisilicate using the isomorphous substi...

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Bibliographic Details
Main Authors: B. Rabindran Jermy, Mohammed Salahuddin, Gazali Tanimu, Hatim Dafalla, Sarah Almofty, Vijaya Ravinayagam
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pharmaceutics
Subjects:
ferrisilicate
PEG
insulin
encapsulation
diabetic mellitus
Online Access:https://www.mdpi.com/1999-4923/15/2/593

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