Glycerophosphocholine provision rescues Candida albicans growth and signaling phenotypes associated with phosphate limitation

Glycerophosphocholine provision rescues Candida albicans growth and signaling phenotypes associated with phosphate limitation

ABSTRACTThe fungal pathogen Candida albicans must acquire phosphate to colonize, infect, and proliferate in the human host. C. albicans has four inorganic phosphate (Pi) transporters, Pho84 being the major high-affinity transporter; its cells can also use glycerophosphocholine (GPC) as their sole ph...

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Bibliographic Details
Main Authors: William R. King, Maikel Acosta-Zaldívar, Wanjun Qi, Nicholas Cherico, Lauren Cooke, Julia R. Köhler, Jana Patton-Vogt
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mSphere
Subjects:
phosphate metabolism
phospholipids
Candida albicans
glycerophosphodiesters
phosphate
cell signaling
Online Access:https://journals.asm.org/doi/10.1128/msphere.00231-23

Internet

https://journals.asm.org/doi/10.1128/msphere.00231-23

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