RNase P-Mediated Sequence-Specific Cleavage of RNA by Engineered External Guide Sequences

The RNA cleavage activity of RNase P can be employed to decrease the levels of specific RNAs and to study their function or even to eradicate pathogens. Two different technologies have been developed to use RNase P as a tool for RNA knockdown. In one of these, an external guide sequence, which mimic...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Merel Derksen, Vicky Mertens, Ger J.M. Pruijn
Format: Artykuł
Język:English
Wydane: MDPI AG 2015-11-01
Seria:Biomolecules
Hasła przedmiotowe:
Dostęp online:http://www.mdpi.com/2218-273X/5/4/3029