Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case report
Ochronosis is a rare autosomal recessive disorder of tyrosine metabolism characterized by multilevel spinal degeneration and arthritis of large weight-bearing joints, which is referred to as ochronotic arthropathy. In this case report, we describe diagnosis and treatment of ochronotic arthropathy in...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-09-01
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| Series: | Frontiers in Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2023.1212580/full |
| _version_ | 1797680820556660736 |
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| author | Yikai Liu Chenkai Li Zian Zhang Xinzhe Lu Haining Zhang |
| author_facet | Yikai Liu Chenkai Li Zian Zhang Xinzhe Lu Haining Zhang |
| author_sort | Yikai Liu |
| collection | DOAJ |
| description | Ochronosis is a rare autosomal recessive disorder of tyrosine metabolism characterized by multilevel spinal degeneration and arthritis of large weight-bearing joints, which is referred to as ochronotic arthropathy. In this case report, we describe diagnosis and treatment of ochronotic arthropathy in a patient who underwent total hip arthroplasty (THA) and total knee arthroplasty (TKA). The Harris hip score was 26 preoperatively and 45, 68, 76, 90, 92, and 94 at 1, 3, 6, 9, 11, and 14 months, respectively, postoperatively. The forgotten joint score (FJS) of the hip was 27.8, 52.8, 81.1, 89.0, 90.6, and 92.4 at 1, 3, 6, 9, 11, and 14 months, respectively, postoperatively. TKA was performed 8 months after THA. The Knee Society Score was 36 before TKA and 74, 82, and 90 at 1, 3, and 6 months, respectively, after TKA. The FJS of the knee was 36.6, 63.9, and 84.5 at 1, 3, and 6 months, respectively, after TKA. The patient’s knee range of motion returned to normal, with significant reduction in pain and improved satisfaction levels after TKA. THA and TKA can achieve good clinical outcomes in patients with ochronosis accompanied by severe joint pain. |
| first_indexed | 2024-03-11T23:35:50Z |
| format | Article |
| id | doaj.art-43e85ead051d41c9a0cb2d8e2a66cce0 |
| institution | Directory Open Access Journal |
| issn | 2296-858X |
| language | English |
| last_indexed | 2024-03-11T23:35:50Z |
| publishDate | 2023-09-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj.art-43e85ead051d41c9a0cb2d8e2a66cce02023-09-20T00:18:35ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2023-09-011010.3389/fmed.2023.12125801212580Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case reportYikai Liu0Chenkai Li1Zian Zhang2Xinzhe Lu3Haining Zhang4Department of Joint Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartment of Orthopedics, Peking Union Medical College, Beijing, ChinaDepartment of Joint Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartment of Joint Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaDepartment of Joint Surgery, The Affiliated Hospital of Qingdao University, Qingdao, ChinaOchronosis is a rare autosomal recessive disorder of tyrosine metabolism characterized by multilevel spinal degeneration and arthritis of large weight-bearing joints, which is referred to as ochronotic arthropathy. In this case report, we describe diagnosis and treatment of ochronotic arthropathy in a patient who underwent total hip arthroplasty (THA) and total knee arthroplasty (TKA). The Harris hip score was 26 preoperatively and 45, 68, 76, 90, 92, and 94 at 1, 3, 6, 9, 11, and 14 months, respectively, postoperatively. The forgotten joint score (FJS) of the hip was 27.8, 52.8, 81.1, 89.0, 90.6, and 92.4 at 1, 3, 6, 9, 11, and 14 months, respectively, postoperatively. TKA was performed 8 months after THA. The Knee Society Score was 36 before TKA and 74, 82, and 90 at 1, 3, and 6 months, respectively, after TKA. The FJS of the knee was 36.6, 63.9, and 84.5 at 1, 3, and 6 months, respectively, after TKA. The patient’s knee range of motion returned to normal, with significant reduction in pain and improved satisfaction levels after TKA. THA and TKA can achieve good clinical outcomes in patients with ochronosis accompanied by severe joint pain.https://www.frontiersin.org/articles/10.3389/fmed.2023.1212580/fullochronotic arthropathytotal hip arthroplastyalkaptonuriatotal knee arthroplastyjoint pain |
| spellingShingle | Yikai Liu Chenkai Li Zian Zhang Xinzhe Lu Haining Zhang Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case report Frontiers in Medicine ochronotic arthropathy total hip arthroplasty alkaptonuria total knee arthroplasty joint pain |
| title | Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case report |
| title_full | Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case report |
| title_fullStr | Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case report |
| title_full_unstemmed | Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case report |
| title_short | Ochronotic arthropathy effectively treated with total hip and total knee arthroplasty: a case report |
| title_sort | ochronotic arthropathy effectively treated with total hip and total knee arthroplasty a case report |
| topic | ochronotic arthropathy total hip arthroplasty alkaptonuria total knee arthroplasty joint pain |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2023.1212580/full |
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