Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population data
Introduction Functional somatic disorders (FSDs) are characterized by persistent and disabling physical symptoms that cannot be attributed to well-defined somatic disorders. In adolescents, the prevalence is around 4-10%. Evidence from adult populations suggests that cortisol plays a role in the de...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Cambridge University Press
2022-06-01
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| Series: | European Psychiatry |
| Subjects: | |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933822010860/type/journal_article |
| _version_ | 1797617634618900480 |
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| author | R. Nyengaard K. Kallesøe M. Rimvall E. Ørnbøl E.M. Olsen V. Wyller C. Rask |
| author_facet | R. Nyengaard K. Kallesøe M. Rimvall E. Ørnbøl E.M. Olsen V. Wyller C. Rask |
| author_sort | R. Nyengaard |
| collection | DOAJ |
| description |
Introduction
Functional somatic disorders (FSDs) are characterized by persistent and disabling physical symptoms that cannot be attributed to well-defined somatic disorders. In adolescents, the prevalence is around 4-10%. Evidence from adult populations suggests that cortisol plays a role in the development and perpetuation of FSDs, but little is known regarding adolescents. As cortisol accumulates in hair over time, hair cortisol concentration (HCC) is a promising new biomarker for long-term physiological stress. Moreover, adult studies have found associations between HCC levels and self-perceived stress.
Objectives
To compare HCC levels between adolescents with severe FSDs and adolescents from the general population. Furthermore, to investigate the association between HCC and self-perceived stress.
Methods
The data are retrieved from two projects: the AHEAD trial, including 91 15-19-year-old adolescents diagnosed with a severe FSD, and the Copenhagen Child Cohort 2000 (CCC2000), including data on 1455 16-17-year-old adolescents. Hair samples were collected for HCC analysis, and web-based questionnaires were used to asses self-perceived stress. Functional somatic symptoms were assessed with the Bodily Distress Syndrome (BDS) checklist.
Results
The data have been collected and will be analysed and presented at the congress.
Conclusions
This study can contribute with knowledge about the potential role of cortisol in FSDs in adolescents, and whether self-perceived stress can be used as a marker for physiological stress measured by HCC. Treatments for adolescents with FSDs still need to be improved. The current study may help to understand whether future treatment strategies should include a greater focus on stress management.
Disclosure
No significant relationships.
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| first_indexed | 2024-03-11T07:57:36Z |
| format | Article |
| id | doaj.art-43e96f3b1b5140e28ecee47b7c7b4728 |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:57:36Z |
| publishDate | 2022-06-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-43e96f3b1b5140e28ecee47b7c7b47282023-11-17T05:05:15ZengCambridge University PressEuropean Psychiatry0924-93381778-35852022-06-0165S428S42810.1192/j.eurpsy.2022.1086Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population dataR. Nyengaard0K. Kallesøe1M. Rimvall2E. Ørnbøl3E.M. Olsen4V. Wyller5C. Rask6Psychiatry, Aarhus University Hospital, Research Unit, Department Of Child And Adolescent Psychiatry, Aarhus N, Denmark Aarhus University, Department Of Clinical Medicine, Aarhus C, DenmarkPsychiatry, Aarhus University Hospital, Research Unit, Department Of Child And Adolescent Psychiatry, Aarhus N, DenmarkMental Health Services, Capital Region of Denmark, Child And Adolescent Mental Health Centre, Hellerup, Denmark Psychiatry Region Zealand, Department Of Child And Adolescent Psychiatry, Roskilde, DenmarkAarhus University Hospital, Research Clinic For Functional Disorders And Psychosomatics, Aarhus N, DenmarkBispebjerg & Frederiksberg Hospital, Centre For Clinical Research And Prevention, Copenhagen N V, Denmark Psychiatric Center Ballerup, Outpatient Clinic For Eating Disorders In Adults, Ballerup, DenmarkAkershus University Hospital, Department Of Pediatric And Adolescent Medicine, Nordbyhagen, Norway University of Oslo, Institute Of Clinical Medicine, Oslo, NorwayPsychiatry, Aarhus University Hospital, Research Unit, Department Of Child And Adolescent Psychiatry, Aarhus N, Denmark Aarhus University, Department Of Clinical Medicine, Aarhus C, Denmark Introduction Functional somatic disorders (FSDs) are characterized by persistent and disabling physical symptoms that cannot be attributed to well-defined somatic disorders. In adolescents, the prevalence is around 4-10%. Evidence from adult populations suggests that cortisol plays a role in the development and perpetuation of FSDs, but little is known regarding adolescents. As cortisol accumulates in hair over time, hair cortisol concentration (HCC) is a promising new biomarker for long-term physiological stress. Moreover, adult studies have found associations between HCC levels and self-perceived stress. Objectives To compare HCC levels between adolescents with severe FSDs and adolescents from the general population. Furthermore, to investigate the association between HCC and self-perceived stress. Methods The data are retrieved from two projects: the AHEAD trial, including 91 15-19-year-old adolescents diagnosed with a severe FSD, and the Copenhagen Child Cohort 2000 (CCC2000), including data on 1455 16-17-year-old adolescents. Hair samples were collected for HCC analysis, and web-based questionnaires were used to asses self-perceived stress. Functional somatic symptoms were assessed with the Bodily Distress Syndrome (BDS) checklist. Results The data have been collected and will be analysed and presented at the congress. Conclusions This study can contribute with knowledge about the potential role of cortisol in FSDs in adolescents, and whether self-perceived stress can be used as a marker for physiological stress measured by HCC. Treatments for adolescents with FSDs still need to be improved. The current study may help to understand whether future treatment strategies should include a greater focus on stress management. Disclosure No significant relationships. https://www.cambridge.org/core/product/identifier/S0924933822010860/type/journal_articlehair cortisolfunctional somatic disorderStressadolescent |
| spellingShingle | R. Nyengaard K. Kallesøe M. Rimvall E. Ørnbøl E.M. Olsen V. Wyller C. Rask Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population data European Psychiatry hair cortisol functional somatic disorder Stress adolescent |
| title | Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population data |
| title_full | Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population data |
| title_fullStr | Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population data |
| title_full_unstemmed | Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population data |
| title_short | Hair cortisol and self-perceived stress in adolescents with functional somatic disorders – a comparison with general population data |
| title_sort | hair cortisol and self perceived stress in adolescents with functional somatic disorders a comparison with general population data |
| topic | hair cortisol functional somatic disorder Stress adolescent |
| url | https://www.cambridge.org/core/product/identifier/S0924933822010860/type/journal_article |
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