Micro-RNA193a-3p Inhibits Breast Cancer Cell Driven Growth of Vascular Endothelial Cells by Altering Secretome and Inhibiting Mitogenesis: Transcriptomic and Functional Evidence

Micro-RNA193a-3p Inhibits Breast Cancer Cell Driven Growth of Vascular Endothelial Cells by Altering Secretome and Inhibiting Mitogenesis: Transcriptomic and Functional Evidence

Breast cancer (BC) cell secretome in the tumor microenvironment (TME) facilitates neo-angiogenesis by promoting vascular endothelial cell (VEC) growth. Drugs that block BC cell growth or angiogenesis can restrict tumor growth and are of clinical relevance. Molecules that can target both BC cell and...

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Bibliographic Details
Main Authors: Giovanna Azzarito, Lisa Kurmann, Brigitte Leeners, Raghvendra K. Dubey
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Cells
Subjects:
angiogenesis
vascular endothelial cells
Micro-RNA
MCF-7
secretome
conditioned medium
Online Access:https://www.mdpi.com/2073-4409/11/19/2967

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