Preparation and evaluation of cytotoxic potential of paclitaxel containing poly-3-hydroxybutyrate-co-3-hydroxyvalarate (PTX/PHBV) nanoparticles

Preparation and evaluation of cytotoxic potential of paclitaxel containing poly-3-hydroxybutyrate-co-3-hydroxyvalarate (PTX/PHBV) nanoparticles

Abstract Paclitaxel (PTX) is a potent anticancer drug. In the present study, PTX was loaded in poly-3-hydroxybutyrate-co-3-hydroxyvalarate (PHBV) to fabricate the PTX/PHBV (drug-loaded) nanoparticles via the nanoprecipitation method. Blank PHBV nanoparticles were also prepared. The drug-encapsulatio...

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Bibliographic Details
Main Authors:	A. Aslam, M. R. Berger, I. Ullah, A. Hameed, F. Masood
Format:	Article
Language:	English
Published:	Instituto Internacional de Ecologia 2023-11-01
Series:	Brazilian Journal of Biology
Subjects:	cancer cytotoxicity MTT paclitaxel PHBV nanoparticles
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1519-69842023000101011&lng=en&tlng=en

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