Inhibition of Rho kinase suppresses capsular contraction following lens injury in mice

Inhibition of Rho kinase suppresses capsular contraction following lens injury in mice

PURPOSE: We investigated the effect of systemic fasudil hydrochloride and an inhibitor of nuclear translocation of myocardin-related transcription factor-A (MRTF-A) on capsular contraction in a puncture-injured lens in mice. MATERIALS AND METHODS: Lens injury of an anterior capsular break was achiev...

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Bibliographic Details
Main Authors: Kana Ichikawa, Sai-Ichi Tanaka, Masayasu Miyajima, Yuka Okada, Shizuya Saika
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Taiwan Journal of Ophthalmology
Subjects:
lens epithelial cell
mouse
myocardin-related transcription factor-a
rho
tissue fibrosis
Online Access:http://www.e-tjo.org/article.asp?issn=2211-5056;year=2020;volume=10;issue=2;spage=100;epage=105;aulast=Ichikawa

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