Evodiamine inhibits EPRS expression to regulate glutamate metabolism and proliferation of oral squamous cell carcinoma cells

Evodiamine inhibits EPRS expression to regulate glutamate metabolism and proliferation of oral squamous cell carcinoma cells

Abstract The effects of evodiamine (EVO) on oral squamous cell carcinoma (OSCC) are not yet understood. Based on our earlier findings, we hypothesized that evodiamine may affect OSCC cell proliferation and glutamate metabolism by modulating the expression of EPRS (glutamyl‐prolyl‐tRNA synthetase 1)....

Bibliografski detalji
Glavni autori:	Li‐Qi Lin, Si‐Yi Lv, Hao‐Zhe Ren, Rong‐Rong Li, Lin Li, Yun‐Qing Pang, Jing Wang
Format:	Članak
Jezik:	English
Izdano:	Wiley 2024-04-01
Serija:	Kaohsiung Journal of Medical Sciences
Teme:	evodiamine glutamate metabolism glutamyl‐prolyl‐tRNA synthetase 1 (EPRS) oral squamous cell carcinoma proliferation
Online pristup:	https://doi.org/10.1002/kjm2.12803

Slični predmeti

HIV-1 Gag Binds the Multi-Aminoacyl-tRNA Synthetase Complex via the EPRS Subunit
od: Danni Jin, i dr.
Izdano: (2023-02-01)

Peroxidase-mimicking evodiamine/indocyanine green nanoliposomes for multimodal imaging-guided theranostics for oral squamous cell carcinoma
od: Zheng Wei, i dr.
Izdano: (2021-07-01)

Inhibitory Effect of Evodiamine on Psoriasis Lesions and Itching in Mice
od: Liang J, i dr.
Izdano: (2024-06-01)

Control of fibrosis with enhanced safety via asymmetric inhibition of prolyl‐tRNA synthetase 1
od: Ina Yoon, i dr.
Izdano: (2023-05-01)

Development of a novel N14-substituted antitumor evodiamine derivative with inhibiting heat shock protein 70 in non-small cell lung cancer
od: Hye-Young Min, i dr.
Izdano: (2024-10-01)

Evodiamine: A Extremely Potential Drug Development Candidate of Alkaloids from Evodia rutaecarpa
od: Lin L, i dr.
Izdano: (2024-09-01)

Maintaining calcium homeostasis as a strategy to alleviate nephrotoxicity caused by evodiamine
od: Chun-qi Yang, i dr.
Izdano: (2024-08-01)

Therapeutic effect of evodiamine on atopic dermatitis in rat models
od: JIANG Su, LYU Xinxiang, CUI Yanhong, LYU Liting, LI Dongxia
Izdano: (2024-09-01)

Evodiamine inhibits proliferation and induces apoptosis of nasopharyngeal carcinoma cells via the SRC/ERBB2-mediated MAPK/ERK signaling pathway
od: Jie Liu, i dr.
Izdano: (2024-09-01)

Phenotyping mitochondrial glutamyl-tRNA synthetase deficiency (EARS2): A case series and systematic literature review
od: Gonçalo Pelayo, i dr.
Izdano: (2024-10-01)

Adenosine-Mimicking Derivatives of 3-Aminopyrazine-2-Carboxamide: Towards Inhibitors of Prolyl-tRNA Synthetase with Antimycobacterial Activity
od: Vinod Sukanth Kumar Pallabothula, i dr.
Izdano: (2022-10-01)

Induction of Apoptosis and Effect on the FAK/AKT/mTOR Signal Pathway by Evodiamine in Gastric Cancer Cells
od: Ji Yeong Yang, i dr.
Izdano: (2022-09-01)

Molecular Dynamics Simulation of the Complex of PDE5 and Evodiamine
od: Ayame Kobayashi, i dr.
Izdano: (2023-02-01)

Metabolic characteristics of evodiamine were associated with its hepatotoxicity via PPAR/PI3K/AKT/NF-кB/tight junction pathway-mediated apoptosis in zebrafish
od: Qiqi Fan, i dr.
Izdano: (2024-07-01)

Structure-Based Virtual Screening of Potential Inhibitors Targeting the Prolyl-tRNA Synthetase (PRS) in <i>Eimeria tenella</i>: Insights from Molecular Docking, ADMET Studies, and Molecular Dynamics Simulations
od: Haiming Cai, i dr.
Izdano: (2025-02-01)

Salidroside ameliorates cerebral ischemic injury and regulates the glutamate metabolism pathway in astrocytes
od: Xiaoyu Zheng, i dr.
Izdano: (2024-11-01)

Design, synthesis, and biological evaluation of benzenesulfonyl chloride-substituted evodiamine derivatives as potential PGAM1 inhibitors
od: Binbin Wei, i dr.
Izdano: (2023-11-01)

Design, synthesis, and biological evaluation of evodiamine-indolequinone hybrids as novel NQO1 agonists against non-small cell lung cancer
od: BinBin Wei, i dr.
Izdano: (2025-01-01)

Evodiamine inhibits programmed cell death ligand 1 expression via the PI3K/AKT signaling pathway to regulate antitumor immunity in melanoma
od: Jiamin Li, i dr.
Izdano: (2025-02-01)

Isoleucyl-tRNA synthetase 2 promotes pancreatic ductal adenocarcinoma proliferation and metastasis by stabilizing β-catenin
od: Yixun Jin, i dr.
Izdano: (2025-05-01)

Consistent RNA expression and RNA modification patterns in cardiotoxicity induced by Matrine and Evodiamine
od: Guanhua Fang, i dr.
Izdano: (2025-01-01)

Experimental and computational study on anti-gastric cancer activity and mechanism of evodiamine derivatives
od: Jingli Liu, i dr.
Izdano: (2024-05-01)

Phenotypic and Genotypic Variation of Cultivated <i>Panax quinquefolius</i>
od: Abdurraouf Abaya, i dr.
Izdano: (2024-01-01)

Evodiamine Alleviates 2,4-Dinitro-1-Chloro-Benzene-Induced Atopic Dermatitis-like Symptoms in BALB/c Mice
od: So-Young Han, i dr.
Izdano: (2024-04-01)

Evodiamine suppresses endometriosis development induced by early EBV exposure through inhibition of ERβ
od: Junling Wang, i dr.
Izdano: (2024-08-01)

Trypanosoma brucei multi-aminoacyl-tRNA synthetase complex formation limits promiscuous tRNA proofreading
od: Rylan R. Watkins, i dr.
Izdano: (2024-07-01)

Leukoencephalopathy with Brain stem and Spinal cord involvement and Lactate elevation (LBSL): Report of a new family and a novel DARS2 mutation
od: Wei-Lin Huang, i dr.
Izdano: (2024-03-01)

Is Methionyl-tRNA Synthetase Applicable as a Diagnostic Marker for Lung Cancer in Bronchial Ultrasound-Guided Brushing Cells?
od: Kyungjong Lee, i dr.
Izdano: (2021-10-01)

Glutamate Metabolism in Brain Structures in Experimental Hemorrhagic Shock
od: V. N. Jakovlev, i dr.
Izdano: (2017-03-01)

Reversible lysine acetylation regulates nuclear translocation of TyrRS to counteract genotoxic oxidative stress
od: Chaoqun Li, i dr.
Izdano: (2017-05-01)

PHD3 inhibits cell proliferation through hydroxylation of PAX2 at proline 9
od: Lun Jie, i dr.
Izdano: (2022-04-01)

A model organism pipeline provides insight into the clinical heterogeneity of TARS1 loss-of-function variants
od: Rebecca Meyer-Schuman, i dr.
Izdano: (2024-07-01)

Protein–Protein Interactions of Seryl-tRNA Synthetases with Emphasis on Human Counterparts and Their Connection to Health and Disease
od: Morana Dulic, i dr.
Izdano: (2024-01-01)

The isolated carboxy‐terminal domain of human mitochondrial leucyl‐tRNA synthetase rescues the pathological phenotype of mitochondrial tRNA mutations in human cells
od: Elena Perli, i dr.
Izdano: (2014-01-01)

Aminoacyl‐tRNA synthetases in medicine and disease
od: Peng Yao, i dr.
Izdano: (2013-02-01)

The Aminoacyl-tRNA Synthetase and tRNA Expression Levels Are Deregulated in Cancer and Correlate Independently with Patient Survival
od: Anmolpreet Kaur Sangha, i dr.
Izdano: (2022-07-01)

DWN12088, A Prolyl-tRNA Synthetase Inhibitor, Alleviates Hepatic Injury in Nonalcoholic Steatohepatitis
od: Dong-Keon Lee, i dr.
Izdano: (2024-01-01)

A Pair of Compound Heterozygous <i>IARS2</i> Variants Manifesting West Syndrome and Electrolyte Disorders in a Chinese Patient
od: Feiyu Zhou, i dr.
Izdano: (2024-01-01)

Interplay between mistranslation and oxidative stress in Escherichia coli
od: Ević Valentina, i dr.
Izdano: (2024-06-01)

The Ability of the EPR MOUSE to Study Underpaintings
od: Stanley E. Liang, i dr.
Izdano: (2023-07-01)