Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer

Abstract Background Ovarian cancer is the most lethal gynaecological malignancy. Chemotherapy is the main stay of treatment for metastatic disease, with modest response rates but significant side effects. Therefore, there is a need for alternative therapies that can control the disease while offerin...

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Autors principals:	Karen K. L. Chan, Michelle K. Y. Siu, Yu-xin Jiang, Jing-jing Wang, Thomas H. Y. Leung, Hextan Y. S. Ngan
Format:	Article
Idioma:	English
Publicat:	BMC 2018-05-01
Col·lecció:	Cancer Cell International
Matèries:	Genistein Daidzein ERB-041 Ovarian cancer
Accés en línia:	http://link.springer.com/article/10.1186/s12935-018-0559-2

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