Entrainment and maintenance of an internal metronome in supplementary motor area
To prepare timely motor actions, we constantly predict future events. Regularly repeating events are often perceived as a rhythm to which we can readily synchronize our movements, just as in dancing to music. However, the neuronal mechanisms underlying the capacity to encode and maintain rhythms are...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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eLife Sciences Publications Ltd
2018-10-01
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| Series: | eLife |
| Subjects: | |
| Online Access: | https://elifesciences.org/articles/38983 |
| _version_ | 1811180595027378176 |
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| author | Jaime Cadena-Valencia Otto García-Garibay Hugo Merchant Mehrdad Jazayeri Victor de Lafuente |
| author_facet | Jaime Cadena-Valencia Otto García-Garibay Hugo Merchant Mehrdad Jazayeri Victor de Lafuente |
| author_sort | Jaime Cadena-Valencia |
| collection | DOAJ |
| description | To prepare timely motor actions, we constantly predict future events. Regularly repeating events are often perceived as a rhythm to which we can readily synchronize our movements, just as in dancing to music. However, the neuronal mechanisms underlying the capacity to encode and maintain rhythms are not understood. We trained nonhuman primates to maintain the rhythm of a visual metronome of diverse tempos and recorded neural activity in the supplementary motor area (SMA). SMA exhibited rhythmic bursts of gamma band (30–40 Hz) reflecting an internal tempo that matched the extinguished visual metronome. Moreover, gamma amplitude increased throughout the trial, providing an estimate of total elapsed time. Notably, the timing of gamma bursts and firing rate modulations allowed predicting whether monkeys were ahead or behind the correct tempo. Our results indicate that SMA uses dynamic motor plans to encode a metronome for rhythms and a stopwatch for total elapsed time. |
| first_indexed | 2024-04-11T09:06:00Z |
| format | Article |
| id | doaj.art-43f1ddc92c4541a99c44765aed3e927a |
| institution | Directory Open Access Journal |
| issn | 2050-084X |
| language | English |
| last_indexed | 2024-04-11T09:06:00Z |
| publishDate | 2018-10-01 |
| publisher | eLife Sciences Publications Ltd |
| record_format | Article |
| series | eLife |
| spelling | doaj.art-43f1ddc92c4541a99c44765aed3e927a2022-12-22T04:32:39ZengeLife Sciences Publications LtdeLife2050-084X2018-10-01710.7554/eLife.38983Entrainment and maintenance of an internal metronome in supplementary motor areaJaime Cadena-Valencia0Otto García-Garibay1Hugo Merchant2https://orcid.org/0000-0002-3488-9501Mehrdad Jazayeri3Victor de Lafuente4https://orcid.org/0000-0002-1047-1354Institute of Neurobiology, National Autonomous University of Mexico, Querétaro, MéxicoInstitute of Neurobiology, National Autonomous University of Mexico, Querétaro, MéxicoInstitute of Neurobiology, National Autonomous University of Mexico, Querétaro, MéxicoMcGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, United StatesInstitute of Neurobiology, National Autonomous University of Mexico, Querétaro, MéxicoTo prepare timely motor actions, we constantly predict future events. Regularly repeating events are often perceived as a rhythm to which we can readily synchronize our movements, just as in dancing to music. However, the neuronal mechanisms underlying the capacity to encode and maintain rhythms are not understood. We trained nonhuman primates to maintain the rhythm of a visual metronome of diverse tempos and recorded neural activity in the supplementary motor area (SMA). SMA exhibited rhythmic bursts of gamma band (30–40 Hz) reflecting an internal tempo that matched the extinguished visual metronome. Moreover, gamma amplitude increased throughout the trial, providing an estimate of total elapsed time. Notably, the timing of gamma bursts and firing rate modulations allowed predicting whether monkeys were ahead or behind the correct tempo. Our results indicate that SMA uses dynamic motor plans to encode a metronome for rhythms and a stopwatch for total elapsed time.https://elifesciences.org/articles/38983rhythm perceptionsupplementary motor arealocal field potentialprimatetiming |
| spellingShingle | Jaime Cadena-Valencia Otto García-Garibay Hugo Merchant Mehrdad Jazayeri Victor de Lafuente Entrainment and maintenance of an internal metronome in supplementary motor area eLife rhythm perception supplementary motor area local field potential primate timing |
| title | Entrainment and maintenance of an internal metronome in supplementary motor area |
| title_full | Entrainment and maintenance of an internal metronome in supplementary motor area |
| title_fullStr | Entrainment and maintenance of an internal metronome in supplementary motor area |
| title_full_unstemmed | Entrainment and maintenance of an internal metronome in supplementary motor area |
| title_short | Entrainment and maintenance of an internal metronome in supplementary motor area |
| title_sort | entrainment and maintenance of an internal metronome in supplementary motor area |
| topic | rhythm perception supplementary motor area local field potential primate timing |
| url | https://elifesciences.org/articles/38983 |
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