A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipients
Acute kidney injury (AKI) is the second prevalent organ damage among COVID-19 infected individuals, which mainly affects those with critical diseases or underlying kidney disorders. Emerging data have suggested that AKI is associated with adverse outcomes, severe COVID-19 disease, and high mortality...
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| Format: | Article |
| Language: | English |
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Society of Diabetic Nephropathy Prevention
2022-09-01
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| Series: | Journal of Nephropathology |
| Subjects: | |
| Online Access: | https://nephropathol.com/PDF/jnp-11-e18392.pdf |
| _version_ | 1797828036602626048 |
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| author | Amirhossein Parsaei Soroush Moradi Hanie Karimi Abdolkarim Haji Ghadery Behnam Amini Anahita Najafi Mahnaz Momenzadeh Leila Mostafavi Jyoti Baharani |
| author_facet | Amirhossein Parsaei Soroush Moradi Hanie Karimi Abdolkarim Haji Ghadery Behnam Amini Anahita Najafi Mahnaz Momenzadeh Leila Mostafavi Jyoti Baharani |
| author_sort | Amirhossein Parsaei |
| collection | DOAJ |
| description | Acute kidney injury (AKI) is the second prevalent organ damage among COVID-19 infected individuals, which mainly affects those with critical diseases or underlying kidney disorders. Emerging data have suggested that AKI is associated with adverse outcomes, severe COVID-19 disease, and high mortality. However, the true nature and pathophysiology of COVID-19-associated kidney injury, and its effect on patients with underlying kidney diseases and transplant recipients, still remains controversial. Accordingly, this review study aimed primarily to describe the history of AKI in COVID-19 infected patients and to achieve a robust understanding of the latest findings on the mechanism of the injury. Secondly, this systematic and precise review of the literature concerning the aspects of AKI in infected patients with chronic kidney disease and transplant recipients provided a comprehensive report of mortality in these individuals. Finally, the present research suggested the possible protective measures that physicians can take to prevent, control, and treat this condition. Our study paves the way for future works with a more robust methodology to better understand COVID-19-related kidney injury |
| first_indexed | 2024-04-09T12:58:02Z |
| format | Article |
| id | doaj.art-43f1eb9e5a4c4a519407ebe84797959c |
| institution | Directory Open Access Journal |
| issn | 2251-8363 2251-8819 |
| language | English |
| last_indexed | 2024-04-09T12:58:02Z |
| publishDate | 2022-09-01 |
| publisher | Society of Diabetic Nephropathy Prevention |
| record_format | Article |
| series | Journal of Nephropathology |
| spelling | doaj.art-43f1eb9e5a4c4a519407ebe84797959c2023-05-13T11:01:32ZengSociety of Diabetic Nephropathy PreventionJournal of Nephropathology2251-83632251-88192022-09-01114e18392e1839210.34172/jnp.2022.18392jnp-18392A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipientsAmirhossein Parsaei0Soroush Moradi1Hanie Karimi2Abdolkarim Haji Ghadery3Behnam Amini4Anahita Najafi5Mahnaz Momenzadeh6Leila Mostafavi7Jyoti Baharani8Non-Communicable Diseases Research Center, Tehran University of Medical Sciences, Tehran, IranNon-Communicable Diseases Research Center, Tehran University of Medical Sciences, Tehran, IranFaculty of Medicine, Tehran University of Medical Science, Tehran, IranFaculty of Medicine, Tehran University of Medical Science, Tehran, IranFaculty of Medicine, Tehran University of Medical Science, Tehran, IranFaculty of Medicine, Tehran University of Medical Science, Tehran, IranNickan Research Institute, Isfahan, IranDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USAUniversity Hospitals Birmingham B95SS, United KingdomAcute kidney injury (AKI) is the second prevalent organ damage among COVID-19 infected individuals, which mainly affects those with critical diseases or underlying kidney disorders. Emerging data have suggested that AKI is associated with adverse outcomes, severe COVID-19 disease, and high mortality. However, the true nature and pathophysiology of COVID-19-associated kidney injury, and its effect on patients with underlying kidney diseases and transplant recipients, still remains controversial. Accordingly, this review study aimed primarily to describe the history of AKI in COVID-19 infected patients and to achieve a robust understanding of the latest findings on the mechanism of the injury. Secondly, this systematic and precise review of the literature concerning the aspects of AKI in infected patients with chronic kidney disease and transplant recipients provided a comprehensive report of mortality in these individuals. Finally, the present research suggested the possible protective measures that physicians can take to prevent, control, and treat this condition. Our study paves the way for future works with a more robust methodology to better understand COVID-19-related kidney injuryhttps://nephropathol.com/PDF/jnp-11-e18392.pdfacute kidney injurycovid-19akitransplant recipients |
| spellingShingle | Amirhossein Parsaei Soroush Moradi Hanie Karimi Abdolkarim Haji Ghadery Behnam Amini Anahita Najafi Mahnaz Momenzadeh Leila Mostafavi Jyoti Baharani A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipients Journal of Nephropathology acute kidney injury covid-19 aki transplant recipients |
| title | A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipients |
| title_full | A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipients |
| title_fullStr | A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipients |
| title_full_unstemmed | A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipients |
| title_short | A review of pathophysiology, mortality, risk factors and protective measures of acute kidney injury in COVID-19 patients with underlying kidney disease and kidney transplant recipients |
| title_sort | review of pathophysiology mortality risk factors and protective measures of acute kidney injury in covid 19 patients with underlying kidney disease and kidney transplant recipients |
| topic | acute kidney injury covid-19 aki transplant recipients |
| url | https://nephropathol.com/PDF/jnp-11-e18392.pdf |
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