Lack of association between bridging integrator 1 (BIN1) rs744373 polymorphism and tau‐PET load in cognitively intact older adults

Lack of association between bridging integrator 1 (BIN1) rs744373 polymorphism and tau‐PET load in cognitively intact older adults

Abstract Introduction The bridging integrator 1(BIN1) rs744373 risk polymorphism has been linked to increased [18F]AV1451 signal in non‐demented older adults (ie., mild cognitive impairment [MCI] plus cognitively normal [CN] individuals). However, the association of BIN1 with in vivo tau, amyloid be...

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Main Authors: Jolien Schaeverbeke, Emma S Luckett, Silvy Gabel, Mariska Reinartz, Steffi De Meyer, Isabelle Cleynen, Kristel Sleegers, Christine Van Broeckhoven, Guy Bormans, Kim Serdons, Koen Van Laere, Patrick Dupont, Rik Vandenberghe, and the Alzheimer's Disease Neuroimaging Initiative**
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Alzheimer’s & Dementia: Translational Research & Clinical Interventions
Subjects:
ADNI
APOE
BIN1 rs744373
F‐PACK
MCI
PET
Online Access:https://doi.org/10.1002/trc2.12227

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