Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis

Serum biomarkers of neuroinflammation and blood-brain barrier leakage in amyotrophic lateral sclerosis

Abstract Amyotrophic lateral sclerosis (ALS) is an incurable and rapidly progressive neurological disorder. Biomarkers are critical to understanding disease causation, monitoring disease progression and assessing the efficacy of treatments. However, robust peripheral biomarkers are yet to be identif...

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Bibliographic Details
Main Authors: Maize C. Cao, Erin E. Cawston, Grace Chen, Collin Brooks, Jeroen Douwes, Dave McLean, E. Scott Graham, Mike Dragunow, Emma L. Scotter
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Neurology
Subjects:
Amyotrophic lateral sclerosis
Serum
Cytokine
Blood-brain barrier
Neuroinflammation
Online Access:https://doi.org/10.1186/s12883-022-02730-1

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