The effects of sodium butyrate supplementation on the expression levels of PGC-1α, PPARα, and UCP-1 genes, serum level of GLP-1, metabolic parameters, and anthropometric indices in obese individuals on weight loss diet: a study protocol for a triple-blind, randomized, placebo-controlled clinical trial

The effects of sodium butyrate supplementation on the expression levels of PGC-1α, PPARα, and UCP-1 genes, serum level of GLP-1, metabolic parameters, and anthropometric indices in obese individuals on weight loss diet: a study protocol for a triple-blind, randomized, placebo-controlled clinical trial

Abstract Background Obesity is a multifaceted disease characterized by an abnormal accumulation of adipose tissue. Growing evidence has proposed microbiota-derived metabolites as a potential factor in the pathophysiology of obesity and related metabolic conditions over the last decade. As one of the...

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Bibliographic Details
Main Authors: Parichehr Amiri, Seyed Ahmad Hosseini, Neda Roshanravan, Maryam Saghafi-Asl, Mitra Tootoonchian
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Trials
Subjects:
Sodium butyrate
Obesity
Energy metabolism genes
Appetite
Randomized controlled trial
Online Access:https://doi.org/10.1186/s13063-022-06891-9

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